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  1. In many clinical conditions that involve free flaps and tissue transplantations the possibility of minimizing ischemia-reperfusion injury can be a determinant factor for the success of the surgery itself. We h...

    Authors: Claudia Claroni, Giulia Torregiani, Marco Covotta, Maria Sofra, Alessandra Scotto Di Uccio, Maria E. Marcelli, Alessia Naccarato and Ester Forastiere
    Citation: BMC Anesthesiology 2016 16:66
  2. We conducted a prospective, randomized, multicenter study to evaluate the differences in the blocking effect of different doses of rocuronium between sevoflurane- or propofol-remifentanil anesthesia in an Asia...

    Authors: Sangseok Lee, Young Jin Ro, Won Uk Koh, Tomoki Nishiyama and Hong-seuk Yang
    Citation: BMC Anesthesiology 2016 16:65
  3. The quality of patients’ recovery following surgery and anesthesia has been a matter of focus and concern over the past decade. The Quality of Recovery-40 (QoR-40) questionnaire was developed and validated for...

    Authors: Siriporn Pitimana-aree, Suthipol Udompanthurak, Saowaphak Lapmahapaisan, Matula Tareerath and Aungsumat Wangdee
    Citation: BMC Anesthesiology 2016 16:64
  4. Class II phosphoinositide 3-kinase α-isoform (PI3K-C2α) is involved in regulating KCl-induced vascular smooth muscle contraction. The current study was to investigate the effects of sevoflurane (SEVO) and isof...

    Authors: Shaozhong Yang, Qi Wu, Shanshan Huang, Zi Wang and Feng Qi
    Citation: BMC Anesthesiology 2016 16:63
  5. Increased central venous pressure secondary to an increase in intraabdominal pressure has been reported during laparoscopic surgery. However, no study has yet determined the effect of pneumoperitoneum on cross...

    Authors: Hüseyin Ulaş Pınar, Rafi Doğan, Ümmü Mine Konuk, Egemen Çifci, Enes Duman, Erdal Karagülle, Emin Türk and Ömer Karaca
    Citation: BMC Anesthesiology 2016 16:62
  6. Hypoxia-inducible-factor-1α (HIF-1α) and HIF-1 degrading prolyl-hydroxylases (PHD) are key regulators of the hypoxic-inflammatory response. Functionally active genetic variants in the HIF-1α (C/T; Single Nucleoti...

    Authors: Annika Höcker, Miriam Rabeling, Alexandra Bick, Linda Cox, Maximiliane Kreuzer, Andrea Engler, Kai Walstein, Hagen S. Bachmann, Karl-Heinz Jöckel, Lewin Eisele, Michael Adamzik, Jürgen Peters and Simon T. Schäfer
    Citation: BMC Anesthesiology 2016 16:61
  7. Mortality from anaesthesia and surgery in many countries in Sub-Saharan Africa remain at levels last seen in high-income countries 70 years ago. With many factors contributing to these poor outcomes, the World...

    Authors: Isabella Epiu, Jossy Verel Bahe Tindimwebwa, Cephas Mijumbi, Francois Ndarugirire, Theogene Twagirumugabe, Edwin Rwebusiga Lugazia, Gerald Dubowitz and Thomas M. Chokwe
    Citation: BMC Anesthesiology 2016 16:60
  8. Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn...

    Authors: Weihua Cai, Jing Cao, Xiuhua Ren, Liang Qiao, Xuemei Chen, Ming Li and Weidong Zang
    Citation: BMC Anesthesiology 2016 16:59
  9. Whether during spontaneous breathing arterial pressure variations (APV) can detect a volume deficit is not established. We hypothesized that amplification of intra-thoracic pressure oscillations by breathing t...

    Authors: Michael Dahl, Chris Hayes, Bodil Steen Rasmussen, Anders Larsson and Niels H. Secher
    Citation: BMC Anesthesiology 2016 16:58
  10. The sniffing position (neck flexion by head elevation and head extension) is commonly used for insertion of a laryngeal mask airway. However, the appropriate degrees of head elevation and head extension are un...

    Authors: Mi-jung Yun, Jung-Won Hwang, Sung-Hoon Kim, Hyo-Ju Hong, Young-Tae Jeon and Hee-Pyoung Park
    Citation: BMC Anesthesiology 2016 16:57
  11. Ramosetron is a relatively new 5-hydroxytryptamine three receptor antagonist with higher binding affinity and more prolonged duration of action compared to ondansetron. The present study was performed to evalu...

    Authors: Tae Kyong Kim, Youn Joung Cho, Chae-won Lim, Jeong Jin Min, Eue-Keun Choi, Deok Man Hong and Yunseok Jeon
    Citation: BMC Anesthesiology 2016 16:56
  12. Despite international data indicating that Enhanced Recovery After Surgery (ERAS) programs, which combine evidence-based perioperative strategies, expedite recovery after surgery, few centers have successfully...

    Authors: Ankit Sarin, Erik S. Litonius, Ramana Naidu, C. Spencer Yost, Madhulika G. Varma and Lee-lynn Chen
    Citation: BMC Anesthesiology 2016 16:55
  13. Intravenous glutamate reduced the risk of developing severe circulatory failure after isolated coronary artery bypass graft surgery (CABG) for acute coronary syndrome (ACS) in a double-blind randomised clinica...

    Authors: Mårten Vidlund, Bashir Tajik, Erik Håkanson, Örjan Friberg, Jonas Holm, Farkas Vanky and Rolf Svedjeholm
    Citation: BMC Anesthesiology 2016 16:54
  14. Images evoked immediately before the induction of anesthesia by means of suggestions may influence dreaming during anesthesia. This study is a retrospective re-evaluation of the original prospective randomized...

    Authors: Judit Gyulaházi, Pál Redl, Zsolt Karányi, Katalin Varga and Béla Fülesdi
    Citation: BMC Anesthesiology 2016 16:53
  15. The purpose of this study was to compare the efficacy and safety of dexmedetomidine versus remifentanil for sedation during awake intubation using a Shikani optical stylet (SOS).

    Authors: Ting Xu, Min Li, Cheng Ni and Xiang-yang Guo
    Citation: BMC Anesthesiology 2016 16:52
  16. We hypothesized that the addition of dexmedetomidine in a clinically relevant dose to propofol-remifentanil anesthesia regimen does not exert an adverse effect on motor-evoked potentials (MEP) and somatosensor...

    Authors: Yan Li, Lingzhong Meng, Yuming Peng, Hui Qiao, Lanjun Guo, Ruquan Han and Adrian W. Gelb
    Citation: BMC Anesthesiology 2016 16:51
  17. Sevoflurane is commonly usedin pediatric anesthesia due to its non-irritating airway properties, and rapid induction and emergence. However, it is associated with emergence agitation (EA) in children. EA may c...

    Authors: Yi Hwa Choi, Kyung Mi Kim, Soo Kyung Lee, Yi Seul Kim, Seon Ju Kim, Woon Suk Hwang and Jin Huan Chung
    Citation: BMC Anesthesiology 2016 16:50
  18. Dexmedetomidine as a sole agent showed limited use for painful procedures due to its insufficient sedative/analgesic effect, pronounced hemodynamic instability and prolonged recovery. The aim of this study was...

    Authors: Eun Hee Chun, Myeong Jae Han, Hee Jung Baik, Hahck Soo Park, Rack Kyung Chung, Jong In Han, Hun Jung Lee and Jong Hak Kim
    Citation: BMC Anesthesiology 2016 16:49
  19. In many countries, routine clinical anaesthesia does not always involve neuromuscular monitoring. In these clinical settings, the efficacy and safety of sugammadex use has not yet been confirmed. We investigat...

    Authors: Eui-Seok Park, Byung Gun Lim, Won-Joon Lee and Il Ok Lee
    Citation: BMC Anesthesiology 2016 16:48
  20. Compared to conventional tidal volume ventilation, low tidal-volume ventilation reduces mortality in cased of acute respiratory distress syndrome. The aim of the present study is to determine whether low tidal...

    Authors: Hitoshi Sato, Kyota Nakamura, Yasuko Baba, Shoko Terada, Takahisa Goto and Kiyoyasu Kurahashi
    Citation: BMC Anesthesiology 2016 16:47
  21. Timely risk stratification is the key strategy to improve prognosis of patients with sepsis. Previous study has proposed to develop a powerful risk assessment rule by the combination of Acute Physiology and Ch...

    Authors: Xuan Liu, Yong Shen, Zhihua Li, Aihua Fei, Hairong Wang, Qinmin Ge and Shuming Pan
    Citation: BMC Anesthesiology 2016 16:46
  22. Interscalene brachial plexus (ISB) block is often associated with phrenic nerve block and diaphragmatic paresis. The goal of our study was to test if the anterior or the posterior ultrasound guided approach of...

    Authors: Lars Bergmann, Stefan Martini, Miriam Kesselmeier, Wolf Armbruster, Thomas Notheisen, Michael Adamzik and RÏ‹diger Eichholz
    Citation: BMC Anesthesiology 2016 16:45
  23. Under the assumption that postoperative nausea and vomiting (PONV) may occur after total hip arthroplasty (THA) regardless of the anesthetic technique used, it is not clear whether general (GA) or spinal (SA) ...

    Authors: Julien Sansonnens, Patrick Taffé and Bernard Burnand
    Citation: BMC Anesthesiology 2016 16:44
  24. Conventionally, ultrasonographic assessment of diaphragm contractility has involved measuring respiratory changes in diaphragm thickness (thickening fraction) using B-mode or caudal displacement with M-mode. T...

    Authors: Sam R. Orde, Andrea J. Boon, Daniel G. Firth, Hector R. Villarraga and Hiroshi Sekiguchi
    Citation: BMC Anesthesiology 2016 16:43
  25. Adequate operation interspace is the premise of laparoscopy, and carbon dioxide (CO2) was an ideal gas for forming lacuna. A retroperitoneal space is used to form operation interspace in retroperitoneal laparosco...

    Authors: Jian-jun Hu, Ya-Hua Liu, Chan-juan Yu and Nuerbolati Jialielihan
    Citation: BMC Anesthesiology 2016 16:42
  26. Ventilation with low tidal volume (VT) is well recognized as a protective approach to patients with acute respiratory distress syndrome (ARDS), but the optimal level of positive end-expiratory pressure (PEEP) rem...

    Authors: Vivian Rotman, Alysson Roncally Carvalho, Rosana Souza Rodrigues, Denise Machado Medeiros, Eduardo Costa Pinto, Fernando Augusto Bozza and Carlos Roberto Ribeiro Carvalho
    Citation: BMC Anesthesiology 2016 16:40
  27. A previous systematic review and meta-analysis reported that omega-3 fatty acids nutrition may reduce mortality in septic patients. As new randomized controlled trials began to accumulate, we conducted an update.

    Authors: Wei Tao, Ping-Song Li, Zhou Shen, Yu-Sheng Shu and Sen Liu
    Citation: BMC Anesthesiology 2016 16:39
  28. Unsatisfactory analgesia for major knee surgery with femoral nerve block (FNB) alone was reported and the additional benefit of sciatic block to continuous femoral nerve block (CFNB) was not conclusive. The ai...

    Authors: Petchara Sundarathiti, Jadesadha Thammasakulsiri, Supawadee Supboon, Supalak Sakdanuwatwong and Molruedee Piangjai
    Citation: BMC Anesthesiology 2016 16:38
  29. The Middle East Respiratory Syndrome coronavirus (MERS-CoV) is an emerging respiratory pathogen with a high mortality rate and no specific treatments available to date. The purpose of this study was to determi...

    Authors: Yaseen M. Arabi, Farhan Al-Enezi, Kajsa-Stina Longuere, Hanan H. Balkhy, Mohamed Al-Sultan, Awad Al-Omari, Fahad M. Al-Hameed, Gail Carson, Nahoko Shindo and Robert Fowler
    Citation: BMC Anesthesiology 2016 16:36
  30. Intracranial pressure (ICP) monitoring is widely used in the management of patients with severe traumatic brain injury (TBI). However, there is limited evidence about the efficacy of ICP monitoring in older su...

    Authors: Wendong You, Junfeng Feng, Qilin Tang, Jun Cao, Lei Wang, Jin Lei, Qing Mao, Guoyi Gao and Jiyao Jiang
    Citation: BMC Anesthesiology 2016 16:35
  31. Placement of a percutaneous coronary sinus catheter (CSC) by an anesthesiologist for retrograde cardioplegia in minimally invasive cardiac surgery is relatively safe in experienced hands. However, the populari...

    Authors: Satoshi Hanada, Hajime Sakamoto, Michael Swerczek and Kenichi Ueda
    Citation: BMC Anesthesiology 2016 16:33
  32. Intravascular fluid shifts, mechanical ventilation and inhalational anesthetic drugs may contribute to intraoperative lung injury. This prospective observational study measured the changes in respiratory imped...

    Authors: Shoko Nakano, Junko Nakahira, Toshiyuki Sawai, Yosuke Kuzukawa, Junichi Ishio and Toshiaki Minami
    Citation: BMC Anesthesiology 2016 16:32
  33. Changes in cardiac power parameters incorporate changes in both aortic flow and blood pressure. We hypothesized that dynamic and non-dynamic cardiac power parameters would track hypovolemia better than equival...

    Authors: Audun Eskeland Rimehaug, Ingrid Elise Hoff, Lars Øivind Høiseth, Jonny Hisdal, Petter Aadahl and Idar Kirkeby-Garstad
    Citation: BMC Anesthesiology 2016 16:31
  34. The insertion of suction devices through endotracheal tubes (ETTs) increases airway resistance and the subsequent suctioning may reduce airway pressures and facilitate atelectasis.

    Authors: Espen R. Nakstad, Helge Opdahl, Fridtjof Heyerdahl, Fredrik Borchsenius and Ole H. Skjønsberg
    Citation: BMC Anesthesiology 2016 16:30
  35. Several factors are believed to influence the development and experience of pain.

    Authors: Morten Sejer Hansen, Jørn Wetterslev, Christian Bressen Pipper, Mohammad Sohail Asghar and Jørgen Berg Dahl
    Citation: BMC Anesthesiology 2016 16:28
  36. The pathogenesis of diabetic neuropathic pain is complicated and its underlying mechanisms remain unclear. Calmodulin-dependent protein kinases (CaMKs) IV (CaMKIV), one of CaMKs, regulates several transcriptio...

    Authors: Xin Zhao, Le Shen, Li Xu, Zhiyao Wang, Chao Ma and Yuguang Huang
    Citation: BMC Anesthesiology 2016 16:27
  37. End stage liver disease (ESLD) is associated with significant thrombotic complications. In this study, we attempted to determine if patients with ESLD, due to oncologic or autoimmune diseases, are susceptible ...

    Authors: Dmitri Bezinover, Khaled Iskandarani, Vernon Chinchilli, Patrick McQuillan, Fuat Saner, Zakiyah Kadry, Thomas R. Riley and Piotr K. Janicki
    Citation: BMC Anesthesiology 2016 16:26
  38. Internationally, there is no consensus on how to best deal with admission requests in cases of full ICU bed occupancy. Knowledge about the degree of dissension and insight into the reasons for this dissension ...

    Authors: Anke J. M. Oerlemans, Hub Wollersheim, Nelleke van Sluisveld, Johannes G. van der Hoeven, Wim J. M. Dekkers and Marieke Zegers
    Citation: BMC Anesthesiology 2016 16:25
  39. Propofol and fentanyl are the most widely administered anesthesia maintaining drugs during colonoscopy. In this study, we determined the median effective concentration (EC50) of propofol required for colonosco...

    Authors: Shiyang Li, Fang Yu, Huichen Zhu, Yuting Yang, Liqun Yang and Jianfeng Lian
    Citation: BMC Anesthesiology 2016 16:24
  40. Ketamine is a commonly used clinical anesthetic and a popular recreational drug. However, with the exception of studies about the nervous system, studies about the effect of early ketamine exposure on embryos ...

    Authors: Ran Guo, Guangjian Liu, Min Du, Yu Shi, Pu Jiang, Xiaoli Liu, Lan Liu, Jianxia Liu and Ying Xu
    Citation: BMC Anesthesiology 2016 16:23
  41. Studies have shown that abdominal girth and vertebral column length have high predictive value for spinal spread after administering a dose of plain bupivacaine. we designed a study to identify the specific co...

    Authors: Qing-he Zhou, Bo Zhu, Chang-na Wei and Min Yan
    Citation: BMC Anesthesiology 2016 16:22
  42. Total hip arthroplasty (THA) is a common procedure associated with moderate postoperative pain. No nerve block without loss of motor function has been documented for THA. We hypothesised that an ultrasound-gui...

    Authors: Kasper H. Thybo, Harald Schmidt and Daniel Hägi-Pedersen
    Citation: BMC Anesthesiology 2016 16:21
  43. The pharmacokinetics and pharmacodynamics of an anesthetic drug may be influenced by gender. The purpose of this study was to compare effect-site half maximal effective concentrations (EC50) of propofol in mal...

    Authors: Jung Ju Choi, Ji Young Kim, Dongchul Lee, Young Jin Chang, Noo Ree Cho and Hyun Jeong Kwak
    Citation: BMC Anesthesiology 2016 16:20
  44. Persistently variable success has been experienced in locally translating even well-grounded national clinical practice guidelines, including in the perioperative setting. We have sought greater applicability ...

    Authors: Thomas R. Vetter, Joydip Barman, Arthur M. Boudreaux and Keith A. Jones
    Citation: BMC Anesthesiology 2016 16:19
  45. The purpose of this randomised, single-centre study was to prospectively investigate the impact of anaesthetic techniques for craniotomy on the release of cytokines IL-6, IL-8, IL-10, and to determine whether ...

    Authors: Jasmina Markovic-Bozic, Blaz Karpe, Iztok Potocnik, Ales Jerin, Andrej Vranic and Vesna Novak-Jankovic
    Citation: BMC Anesthesiology 2016 16:18
  46. Local anesthesia (LA) has been reported to be the best choice for elective open inguinal hernia repair because it is cost efficient, with less post-operative pain and enables more rapid recovery. However, the ...

    Authors: Tao Chen, Yunhe Zhang, Haolu Wang, Qihong Ni, Linhua Yang, Qiwei Li and Jian Wang
    Citation: BMC Anesthesiology 2016 16:17

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