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  1. Content type: Research article

    Dexmedetomidine (DEX) has been used as an anesthetic for decades. The present investigation aimed to elucidate the analgesic impact of DEX on 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced chronic inflammat...

    Authors: Meng Liang, Aijie Shao, Xinsheng Tang, Meiling Feng, Jing Wang and Yingna Qiu

    Citation: BMC Anesthesiology 2019 19:131

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  2. Content type: Research article

    Risk of over-immunosuppression or immunization may mitigate the overall and long-term renal outcomes of kidney transplant recipients (KTR) admitted to the ICU in the modern era but remain poorly described. Thu...

    Authors: Damien Guinault, Arnaud Del Bello, Laurence Lavayssiere, Marie-Béatrice Nogier, Olivier Cointault, Nicolas Congy, Laure Esposito, Anne-Laure Hebral, Olivier Roques, Nassim Kamar and Stanislas Faguer

    Citation: BMC Anesthesiology 2019 19:130

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  3. Content type: Research article

    The efficacy of tranexamic acid (TXA) to reduce perioperative blood loss and allogeneic blood transfusion in cardiac surgeries has been proved in previous studies, but its adverse effects especially seizure ha...

    Authors: Jingfei Guo, Xurong Gao, Yan Ma, Huran Lv, Wenjun Hu, Shijie Zhang, Hongwen Ji, Guyan Wang and Jia Shi

    Citation: BMC Anesthesiology 2019 19:129

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  4. Content type: Case report

    Tricuspid regurgitation (TR) and pulmonary hypertension (PHT) are highly dynamic cardiovascular lesions that may progress rapidly, particularly in the orthotopic liver transplantation (OLT) waitlist population...

    Authors: B. Pearce, R. Hu, F. Desmond, D. Banyasz, R. Jones and C. O. Tan

    Citation: BMC Anesthesiology 2019 19:128

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  5. Content type: Research article

    The levels of tight junction proteins (TJs), especially occludin, correlate with blood-brain barrier (BBB) disruption caused by inflammation in central nervous system (CNS). It has been reported that propofol,...

    Authors: Yue Zhang, Xiaowei Ding, Changhong Miao and Jiawei Chen

    Citation: BMC Anesthesiology 2019 19:127

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  6. Content type: Research article

    We previously reported that each 100 mg dL− 1 reduction in blood glucose over the range from ≈90 to > 300 mg dL− 1 decreases the shivering threshold (triggering core temperature) in rabbits by 1 °C. However, the ...

    Authors: Keiichi Wada, Taishi Masamune, Hirofumi Ino, Kenta Ueda, Tadahiko Ishiyama, Daniel I. Sessler and Takashi Matsukawa

    Citation: BMC Anesthesiology 2019 19:126

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  7. Content type: Research article

    Renal dysfunction following intraoperative arterial hypotension is mainly caused by an insufficient renal blood flow. It is associated with higher mortality and morbidity rates. We hypothesised that the intrao...

    Authors: Patrick Schäfer, Astrid Fahlenkamp, Rolf Rossaint, Mark Coburn and Ana Kowark

    Citation: BMC Anesthesiology 2019 19:125

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  8. Content type: Case report

    Surgical cricothyroidotomy is a last resort in patients with an anticipated difficult airway, but without any guarantee of success. Identification of the cricothyroid membrane may be the key to successful cric...

    Authors: Ippei Jimbo, Kohji Uzawa, Joho Tokumine, Shingo Mitsuda, Kunitaro Watanabe and Tomoko Yorozu

    Citation: BMC Anesthesiology 2019 19:124

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  9. Content type: Research article

    The obstetric airway is a significant cause of maternal morbidity and mortality. Endotracheal intubation is considered the standard of care but the laryngeal mask airway (LMA) has gained acceptance as a rescue...

    Authors: Wei Yu Yao, Shi Yang Li, Yong Jin Yuan, Hon Sen Tan, Nian-Lin R. Han, Rehena Sultana, Pryseley N. Assam, Alex Tiong-Heng Sia and Ban Leong Sng

    Citation: BMC Anesthesiology 2019 19:123

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  10. Content type: Research article

    Obstetric dfficult airway is a leading cause of maternal morbidity and mortality. The laryngeal mask airway (LMA) is often used as a rescue airway device after failed intubation, however, little is known about...

    Authors: Hon Sen Tan, Shi Yang Li, Wei Yu Yao, Yong Jing Yuan, Rehena Sultana, Nian-Lin R. Han, Alex Tiong Heng Sia and Ban Leong Sng

    Citation: BMC Anesthesiology 2019 19:122

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  11. Content type: Research article

    Pharyngeal packing (PP) is commonly performed to reduce the incidence of perioperative blood ingestion (PBI) in nasal surgery (NS), and thus the incidence and severity of postoperative nausea and vomiting (PON...

    Authors: M. Emrah Temel, Tolga Totoz, Kerem Erkalp, Gulen Safiye Temel and Aysin Selcan

    Citation: BMC Anesthesiology 2019 19:121

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  12. Content type: Research article

    There is no defined gold standard for pain management after video-assisted thoracic surgery (VATS) for pneumothorax. In addition to systemic analgesia, various loco-regional analgesic techniques have been prop...

    Authors: Pierre-Antoine Allain, Michele Carella, Apostolos C. Agrafiotis, Julien Burey, Jalal Assouad, El-Mahdi Hafiani, Yacine Ynineb, Francis Bonnet, Marc Garnier and Christophe Quesnel

    Citation: BMC Anesthesiology 2019 19:120

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  13. Content type: Research article

    Quick and complete recovery of cognitive function after general anesthesia is desirable, particularly for working-age patients. Desflurane is less likely to have long-term effects than older-generation inhalat...

    Authors: Ayako Tojo, Kazuhiro Uchimoto, Gaku Inagawa and Takahisa Goto

    Citation: BMC Anesthesiology 2019 19:119

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  14. Content type: Research article

    In the present study, we compare the LMA-Protector™ and the i-gel™ in terms of adequacy of the airway seal, insertion time, ease and accuracy of insertion, and the incidence of postoperative sore throat.

    Authors: Jee-Eun Chang, Hyerim Kim, Jung-Man Lee, Seong-Won Min, Dongwook Won, Kwanghoon Jun and Jin-Young Hwang

    Citation: BMC Anesthesiology 2019 19:118

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  15. Content type: Research article

    Patients undergoing complex spine surgery present with multilevel spinal involvement, advanced age, and multiple comorbidities. Surgery is associated with significant blood loss and remarkable hemodynamic chan...

    Authors: Feng-Cheng Chang, Jr-Rung Lin and Fu-Chao Liu

    Citation: BMC Anesthesiology 2019 19:117

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  16. Content type: Case report

    Maternal cardiac arrest during cesarean section (CS) is an extremely rare but devastating complication. Preventing emergency events from developing into maternal cardiac arrest is one of the most challenging c...

    Authors: Shouming Chen, Lan Wu and Xiaoqin Jiang

    Citation: BMC Anesthesiology 2019 19:116

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  17. Content type: Research article

    Patient satisfaction is a well-established indicator to evaluate the quality of medical care and there is an increasing support for the use of patient-reported experience measures (PREMs) to evaluate satisfact...

    Authors: Wouter Droog, Sanne E. Hoeks, G. Peter van Aggelen, D-Yin Lin, J. Henk Coert, Robert Jan Stolker and Eilish M. Galvin

    Citation: BMC Anesthesiology 2019 19:115

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  18. Content type: Research article

    Peripheral nerve block and local infiltration analgesia (LIA) provide good analgesia after knee replacement. This study evaluated the additional analgesic efficacy of continuous adductor canal block (ACB) adde...

    Authors: Fei Lan, Yanyan Shen, Yanhui Ma, Guanglei Cao, Nicole Philips, Ting Zhang and Tianlong Wang

    Citation: BMC Anesthesiology 2019 19:114

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  19. Content type: Research article

    Several studies have investigated the effects of dexamethasone on post-operative cognitive dysfunction (POCD) or post-operative delirium (POD); however, their conclusions have been inconsistent. Thus, we condu...

    Authors: Li-Qin Li, Cong Wang, Mei-Dan Fang, Hong-Yu Xu, Hong-Liu Lu and Hou-Zhong Zhang

    Citation: BMC Anesthesiology 2019 19:113

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  20. Content type: Research article

    Early extubation after liver transplantation is safe and accelerates patient recovery. Patients with end-stage liver disease undergo sarcopenic changes, and sarcopenia is associated with postoperative morbidit...

    Authors: Min Suk Chae, Jong-Woan Kim, Joon-Yong Jung, Ho Joong Choi, Hyun Sik Chung, Chul Soo Park, Jong Ho Choi and Sang Hyun Hong

    Citation: BMC Anesthesiology 2019 19:112

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  21. Content type: Research article

    To assess the validity of central and pulmonary veno-arterial CO2 gradients to predict fluid responsiveness and to guide fluid management during liver transplantation.

    Authors: Mohamed ELAyashy, Hisham Hosny, Amr Hussein, Ahmed AbdelAal Ahmed Mahmoud, Ahmed Mukhtar, Amira El-Khateeb, Mohamed Wagih, Fawzia AboulFetouh, Amr Abdelaal, Hany Said and Mostafa Abdo

    Citation: BMC Anesthesiology 2019 19:111

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  22. Content type: Research article

    Although PEEP and inversed I:E ratio have been shown to improve gas exchange in ARDS, both can adversely affect systemic hemodynamics and cerebral perfusion. The goal of this study was to assess how changes in...

    Authors: Federica Lovisari, Gergely H. Fodor, Ferenc Peták, Walid Habre and Sam Bayat

    Citation: BMC Anesthesiology 2019 19:110

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  23. Content type: Research article

    Sevoflurane is one of the most frequently used inhaled anesthetics for general anesthesia. Previously it has been reported that at clinically used doses of sevoflurane, cerebral vasoreactivity is maintained. H...

    Authors: Marianna Juhász, Levente Molnár, Béla Fülesdi, Tamás Végh, Dénes Páll and Csilla Molnár

    Citation: BMC Anesthesiology 2019 19:109

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  24. Content type: Research article

    This study aimed at describing usual anesthetic practices for brain-dead donors (BDD) during an organ procurement (OP) procedure and to assess the knowledge and self-confidence of French anesthesiologists with...

    Authors: Benoit Champigneulle, Arthur Neuschwander, Régis Bronchard, Gersende Favé, Julien Josserand, Benjamin Lebas, Olivier Bastien and Romain Pirracchio

    Citation: BMC Anesthesiology 2019 19:108

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  25. Content type: Research article

    Continuous epidural infusion (CEI) has some disadvantages, such as increased local anesthetic consumption and limited area of anesthetic distribution. Programmed intermittent bolus (PIB) is a technique of epid...

    Authors: M. Higashi, K. Shigematsu, E. Nakamori, S. Sakurai and K. Yamaura

    Citation: BMC Anesthesiology 2019 19:107

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  26. Content type: Research article

    Terlipressin, in general, is a vasopressor which acts via V1 receptors. Its infusion elevates mean blood pressure and can reduce bleeding which has a splanchnic origin. The primary outcome was to assess the im...

    Authors: Magdy Mohammed Mahdy, Mostafa Samy Abbas, Emad Zarief Kamel, Mohamed Fathy Mostafa, Ragaa Herdan, Shimaa Abbas Hassan, Ramy Hassan, Ahmed M. Taha, Tameem M. Ibraheem, Bashir A. Fadel, Mohammed Geddawy, Jehan Ahmed Sayed and Osama Ali Ibraheim

    Citation: BMC Anesthesiology 2019 19:106

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  27. Content type: Research article

    The safety and efficiency of intravenous administration of tranexamic acid (TXA) in coronary artery bypass grafting (CABG) remains unconfirmed. Therefore, we conducted a meta-analysis on this topic.

    Authors: Yanting Zhang, Yun Bai, Minmin Chen, Youfa Zhou, Xin Yu, Haiyan Zhou and Gang Chen

    Citation: BMC Anesthesiology 2019 19:104

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  28. Content type: Research article

    Ultrasound guidance might decrease the incidence of local anesthetics systemic toxicity (LAST) for many peripheral nerve blocks compared with nerve stimulator guidance. However, it remains uncertain whether ul...

    Authors: Xu-hao Zhang, Yu-jie Li, Wen-quan He, Chun-yong Yang, Jian-teng Gu, Kai-zhi Lu and Bin Yi

    Citation: BMC Anesthesiology 2019 19:103

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  29. Content type: Research article

    Whether thoracic paravertebral block (PVB) is useful in patients undergoing off-pump coronary artery bypass grafting (OPCABG) remains unknown. This study aimed to investigate the feasibility of bilateral PVB c...

    Authors: Lixin Sun, Qiujie Li, Qiang Wang, Fuguo Ma, Wei Han and Mingshan Wang

    Citation: BMC Anesthesiology 2019 19:101

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  30. Content type: Research article

    Acute kidney injury after cardiac surgery significantly associates with morbidity and mortality. Despite not requiring cardiopulmonary bypass, transcatheter aortic valve replacement patients have an incidence ...

    Authors: Akeel M. Merchant, Javier A. Neyra, Abu Minhajuddin, Lauren E. Wehrmann, Richard A. Mills, Sarah K. Gualano, Dharam J. Kumbhani, Lynn C. Huffman, Michael E. Jessen and Amanda A. Fox

    Citation: BMC Anesthesiology 2019 19:99

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  31. Content type: Research article

    It is still unknown whether newborn infant parasympathetic evaluation (NIPE), based on heart rate variability (HRV) as a reflection of parasympathetic nerve tone, can predict the hemodynamic response to a noci...

    Authors: Kan Zhang, Siyuan Wang, Lei Wu, Yun’an Song, Meihua Cai, Mazhong Zhang and Jijian Zheng

    Citation: BMC Anesthesiology 2019 19:98

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  32. Content type: Research article

    Most centres use fresh frozen plasma (FFP) based protocols to prevent or treat haemostatic disturbances during liver transplantation. In the present study, we used a rotational thrombelastometry (ROTEM™, TEM, ...

    Authors: Matthias Hartmann, Caroline Walde, Daniel Dirkmann and Fuat H. Saner

    Citation: BMC Anesthesiology 2019 19:97

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  33. Content type: Research article

    Postoperative visceral pain is common after surgery and previous studies have demonstrated that oxycodone is an effective treatment. In this study, we compared the effects of preemptive oxycodone to equal dose...

    Authors: Yi An, Lei Zhao, Tianlong Wang, Jiapeng Huang, Wei Xiao, Ping Wang, Lixia Li, Zhongjia Li and Xiaoxu Chen

    Citation: BMC Anesthesiology 2019 19:96

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  34. Content type: Research article

    Insertion of a flexible laryngeal mask airway (LMA Flexible) is known to be more difficult than that of a conventional laryngeal mask airway. The 90° rotation technique can improve the success rate with a conv...

    Authors: Bon-Wook Koo, Ah-Young Oh, Jung-Won Hwang, Hyo-Seok Na and Seong-Won Min

    Citation: BMC Anesthesiology 2019 19:95

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  35. Content type: Research article

    The ultrasound-guided proximal intercostal block (PICB) is performed at the proximal intercostal space (ICS) between the internal intercostal membrane (IIM) and the endothoracic fascia/parietal pleura (EFPP) c...

    Authors: Nantthasorn Zinboonyahgoon, Panya Luksanapruksa, Sitha Piyaselakul, Pawinee Pangthipampai, Suphalerk Lohasammakul, Choopong Luansritisakul, Sunsanee Mali-ong, Nawaporn Sateantantikul, Theera Chueaboonchai and Kamen Vlassakov

    Citation: BMC Anesthesiology 2019 19:94

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  36. Content type: Research article

    Increased lung water and the resultant atelectasis are significant pulmonary complications after cardiopulmonary bypass (CPB) in children undergoing cardiac surgery; these complications are observed after CPB ...

    Authors: Mohamed Elayashy, Mai A. Madkour, Ahmed Abdelaal Ahmed Mahmoud, Hisham Hosny, Amr Hussein, Ahmed Nabih, Ahmed Lofty, Hamza Mohamed Hamza, Passaint Hassan, Mohamed Wagih and Ahmed Kareem Mohamed

    Citation: BMC Anesthesiology 2019 19:93

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  37. Content type: Research article

    Oral cavity and oropharyngeal cancer impose significant threat to airway management. Head and neck radiotherapy (HNRT) may further increase the difficulty of tracheal intubation. We hypothesized that a history...

    Authors: Gang Zheng, Lei Feng and Carol M. Lewis

    Citation: BMC Anesthesiology 2019 19:92

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  38. Content type: Research article

    The purpose of this study was to compare the effects of scalp nerve block (SNB) and local anesthetic infiltration (LA) with 0.75% ropivacaine on postoperative inflammatory response, intraoperative hemodynamic ...

    Authors: Xi Yang, Jing Ma, Ke Li, Lei Chen, Rui Dong, Yayuan Lu, Zongze Zhang and Mian Peng

    Citation: BMC Anesthesiology 2019 19:91

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  39. Content type: Research article

    Hemostasis is the dynamic equilibrium between coagulation and fibrinolysis. During pregnancy, the balance shifts toward a hypercoagulative state; however placental abruption and abnormal placentations may lead...

    Authors: Alessandra Spasiano, Carola Matellon, Daniele Orso, Alessandro Brussa, Maria Cafagna, Anna Marangone, Teresa Dogareschi, Tiziana Bove, Roberta Giacomello, Desrè Fontana, Luigi Vetrugno and Giorgio Della Rocca

    Citation: BMC Anesthesiology 2019 19:90

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  40. Content type: Research article

    Although serum creatinine concentration has been traditionally used as an index of renal function in clinical practice, it is considered relatively inaccurate, especially in patients with mild renal dysfunctio...

    Authors: Myung-Soo Jang, Jae-Sik Nam, Jun-Young Jo, Chang-Hwa Kang, Seung Ah. Ryu, Eun-Ho Lee and In-Cheol Choi

    Citation: BMC Anesthesiology 2019 19:88

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  41. Content type: Research article

    Patient monitoring is critical for perioperative patient safety as anesthesiologists routinely make crucial therapeutic decisions from the information displayed on patient monitors. Previous research has shown...

    Authors: David W. Tscholl, Lucas Handschin, Julian Rössler, Mona Weiss, Donat R. Spahn and Christoph B. Nöthiger

    Citation: BMC Anesthesiology 2019 19:87

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  42. Content type: Research article

    Hypophosphatemia generally occurs in Intensive Care Units (ICUs), but its impact is often ignored. The aim of this study was to investigate whether hypophosphatemia can be a risk factor for ICU 28-day mortality.

    Authors: Lichun Wang, Chaoxing Xiao, Lei Chen, Xiaofei Zhang and Qiuye Kou

    Citation: BMC Anesthesiology 2019 19:86

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  43. Content type: Case report

    Pierre Robin Sequence (PRS) patients are known for their triad of micrognathia, glossoptosis, and airway obstruction. Their airway can be a challenge even for the most experienced pediatric anesthesiologist.

    Authors: Li Zhang, Jian Fei, Jian Jia, Xiaohua Shi, Meimin Qu and Hui Wang

    Citation: BMC Anesthesiology 2019 19:84

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  44. Content type: Case report

    In patients with paroxysmal nocturnal hemoglobinuria (PNH), the membrane-attack complex (MAC) formed on red blood cells (RBCs) causes hemolysis due to the patient’s own activated complement system by an infect...

    Authors: Yuko Kawamoto, Tasuku Nishihara, Aisa Watanabe, Kazuo Nakanishi, Taisuke Hamada, Amane Konishi, Naoki Abe, Sakiko Kitamura, Keizo Ikemune, Yuichiro Toda and Toshihiro Yorozuya

    Citation: BMC Anesthesiology 2019 19:83

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  45. Content type: Case report

    Lung resection after previous contralateral pneumonectomy is rare. We present a case of right anterior segmentectomy despite previous left pneumonectomy, demanding special airway management strategy.

    Authors: Yang Gu, Ruowang Duan, Xin Lv and Jiong Song

    Citation: BMC Anesthesiology 2019 19:82

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