Effect of bevel direction on the success rate of ultrasound-guided radial arterial catheterization

This prospective, single blind, randomized, controlled study was conducted at Seoul National University Bundang Hospital after approval had been obtained from the hospital’s ethics committee (IRB protocol number: B-1201–070–002). Written informed consent include images relating to individual participants was obtained from each participant during a preoperative visit. We explained this is a single-blind study (i.e., subject unaware of group allocation until completion of the study). The study protocol is retrospectively registered with the Korean Clinical Trials Registry (KCT0001711).

Between April 2014 and September 2014, patients between 18 and 80 years of age with an American Society of Anesthesiologists physical status score between I–III and who required radial arterial catheterization for continuous blood pressure monitoring under general anesthesia, were enrolled. Patients with a history of atherosclerosis, hemorrhagic shock, morbid obesity, Raynaud’s disease, or peripheral vascular disease were excluded. Subjects were allocated to either the bevel-up (bevel facing upwards) or bevel-down (bevel facing downwards) group by block randomization. Random numbers generated using a computer-generated randomization table were sealed in an opaque envelope. An operator with experience of more than 100 US-guided radial artery catheterization procedures performed the cannulation.

Following induction of general anesthesia, radial arterial catheterization was performed. With the arm in supination, the wrist was extended over a roll with the hand dorsiflexed at 45°. An observer recorded the time taken (using a stopwatch) by the anesthesiologists to achieve successful US-guided radial artery catheterization. Following antiseptic preparation of the insertion site, an US probe connected to a US system (S-nerve™; Sonosite, Bothell, WA, USA) was used to identify the radial artery in the short-axis view. Using a short-axis approach, a 20-gauge intravenous cannula (BD Angiocath Plus™; Becton Dickinson Medical [S] Pte Ltd, Tuas, Singapore) was placed beneath the center of the transducer at an angle of 30–45°; no local anesthetic was administered prior to catheterization. The puncture needle was inserted with the bevel facing upward in the bevel-up group, and downward in the bevel-down group. When the needle was inserted into a radial artery, an image of its tip appeared on the US screen as a dot within the lumen of the vessel (Fig. 1). Entry of the needle into the artery was indicated by adequate return of free-flowing arterial blood. The diameter (Fig. 2) and depth of the artery (Fig. 3) (the latter defined as the distance from the skin to the outer wall of the artery) were measured from the US image.

Insertion time, defined as the time between the US probe contacting the skin and the placing of the catheter into the radial artery and the number of attempts, were recorded. The ease of insertion was indexed by the success rate on the first attempt. Total success rate, first attempt success rate, second attempt success rate, third attempt success rate, and failure rate in both groups were recorded. Failure of cannulation was defined as more than three attempts at cannulation, because of the possibility for numerous attempts. New attempt was defined as a new penetration of the skin with the needle, followed by an unlimited number of redirections under the skin, as needed. A new catheter was required for new attempt.

Complications including thrombosis, hematoma, vasospasm and posterior wall damage were recorded by an observer. Complications was monitored and detected on US image clinically during and after radial arterial cannulation by an observer (Fig. 4).

US-guided radial artery cannulation under the short-axis view was more successful on the first attempt using the bevel-down approach, which was also associated with reduced insertion time and posterior wall puncture. The effect of bevel direction under US-guided vascular access has not previously been investigated during radial artery catheterization. The bevel-down approach is associated with reduced posterior wall hematoma during internal jugular vein catheterization compared to the bevel-up approach [7]. The incidence of posterior wall puncture using the short-axis approach is reportedly between 31 % and 56 % [6, 8] although in our study the incidence was lower. It appears that the bevel-down approach could facilitate the avoidance of posterior radial arterial wall injury during US-guided radial arterial catheterization. We suspect that a similar mechanism might be involved in arterial line cannulation. The average diameter of the radial artery is approximately 2.5 mm, while the bevel length at the distal end of the needle is 1.1 mm, with the needle tip cut obliquely at an acute angle. There appears to be insufficient space between the needle tip and posterior vessel wall. We speculate that sharp tips may be more likely to transfix the artery using the bevel-up approach.

The long-axis approach affords improved visualization of the needle tip at the time of puncture [5]. It is often difficult to maintain visualization of the needle tip when performing a procedure using the short axis [5]. However, the short-axis approach, which was used in the present study, benefits from the fact that novice users can locate the vessel more easily and achieve vascular access more rapidly compared to the long-axis approach [2]. Users also rated the short-axis approach as being more straightforward, although not significantly. Several measures to increase the success rate of the short-axis approach have been suggested. These include using a visible marker (i.e., a suture on the midpoint of the US probe) [9]. Subcutaneous injection of saline also improves the success rate of the short-axis method in pediatric patients [10]. However, such measures require additional interventions. We suggest that merely changing the bevel direction might improve the success rate and reduce the incidence of posterior wall hematoma. Moreover, our method can be applied to already-established techniques. Accidental hematoma of the posterior wall of the radial artery may occur due to other factors such as the ability of the operator, characteristics of ultrasound equipment, distance from needle entry to transducer, or other factors [5]. Further studies are necessary to prospectively compare complication rates, particularly posterior radial artery wall penetration, of both approaches during US-guided radial arterial catheterization.

A limitation of our study was that the operator could not be blinded to the type of cannulation technique, which represents a possible source of bias. Still another potential limitation was that cannulation was performed by an experienced operator; results achieved might not be applicable to novice users. A third limitation was not including challenging cases, such as peripheral vascular disease patients due to concern of radial arterial catheterization related vascular infarct and thrombosis. All of these might prevent full generalization of our results. We also excluded the more difficult to catheterize patients such as those who were obese. Patients in shock or with low blood pressure were not included.

A larger study population may be needed to demonstrate the benefit of using the bevel down approach during US-guided radial arterial catheterization for challenging cases.

We conclude that the use of the bevel-down approach during US-guided radial artery cannulation under a short-axis view improves the first-attempt success rate compared to the bevel-up approach. The bevel-down technique is associated with reduced insertion time and posterior wall hematoma.

ASA, American society of anesthesiologist; BMI, body mass index; CI, confidence interval; IQR, interquartile range; US, ultrasound