Articles

Letter to the editor: Reply

Authors: Jung-Woo Shim and Min Suk Chae

Comment on “Comparison of analgesic efficacy between rectus sheath blockade, intrathecal morphine with bupivacaine, and intravenous patient-controlled analgesia in patients undergoing robot-assisted laparoscopic prostatectomy: a prospective, observational clinical study”

Authors: Lukas M. Löffel, Dominique Engel and Patrick Y. Wuethrich

Effects of sevoflurane anesthesia and abdominal surgery on the systemic metabolome: a prospective observational study

Metabolic status can be impacted by general anesthesia and surgery. However, the exact effects of general anesthesia and surgery on systemic metabolome remain unclear, which might contribute to postoperative o...

Authors: Yiyong Wei, Donghang Zhang, Jin Liu, Mengchan Ou, Peng Liang, Yunxia Zuo and Cheng Zhou

TNF-α - mediated peripheral and central inflammation are associated with increased incidence of PND in acute postoperative pain

Acute postoperative pain plays an important role in the perioperative neurocognitive disorders (PND). The pathogenesis of PND is still unknown, but it is generally believed that peripheral and central nervous ...

Authors: Yu-fan Zhao, Hui-wen Yang, Ting-shun Yang, Wenxiu Xie and Zhong-hua Hu

Correction to: General anaesthesia related mortality in a limited resource settings region: a retrospective study in two teaching hospitals of Butembo

An amendment to this paper has been published and can be accessed via the original article.

Authors: Furaha Nzanzu Blaise Pascal, Agnes Malisawa, Andreas Barratt-Due, Felix Namboya and Gregor Pollach

Parallel veno-venous and veno-arterial extracorporeal membrane circuits for coexisting refractory hypoxemia and cardiovascular failure: a case report

The complexity of extracorporeal membrane oxygenation (ECMO) techniques continues to evolve. Different cannulation methods and configurations have been proposed as a response to a challenging cardiovascular an...

Authors: Jose R. Navas-Blanco, Sofia A. Lifgren, Roman Dudaryk, Jeffrey Scott, Matthias Loebe and Ali Ghodsizad

Cognitive status of patients judged fit for discharge from the post-anaesthesia care unit after general anaesthesia: a randomized comparison between desflurane and propofol

The Aldrete’s score is used to determine when a patient can safely leave the Post-Anaesthesia Care Unit (PACU) and be transferred to the surgical ward. The Aldrete score is based on the evaluation of vital sig...

Authors: Cyrille Robert, Anne Soulier, Didier Sciard, Guillaume Dufour, Corinne Alberti, Priscilla Boizeau and Marc Beaussier

Improvement of analgesic efficacy for total hip arthroplasty by a modified ultrasound‐guided supra‐inguinal fascia iliaca compartment block

Fascia iliaca compartment block (FICB) is an anterior approach to the lumbar plexus block and provides the effective adjunctive analgesia for total hip arthroplasty (THA).

Authors: Ting Zheng, Bin Hu, Chun-ying Zheng, Feng-yi Huang, Fei Gao and Xiao-chun Zheng

Pathway for enhanced recovery after spinal surgery-a systematic review of evidence for use of individual components

Enhanced recovery in spinal surgery (ERSS) has shown promising improvements in clinical and economical outcomes. We have proposed an ERSS pathway based on available evidence. We aimed to delineate the clinical...

Authors: Ana Licina, Andrew Silvers, Harry Laughlin, Jeremy Russell and Crispin Wan

Conversion of an oral to nasal intubation in difficult nasal anatomy patients: two case reports

Nasal intubation is indispensable for some cases that require intraoral surgical access, and the fiberoptic bronchoscope is the best tool for difficult airways. However, fiberoptic bronchoscopy is not always p...

Authors: Dong Won Kim, Kyu Nam Kim, Jung Eun Sun and Hyun Jin Lim

Anesthetics may modulate cancer surgical outcome: a possible role of miRNAs regulation

microRNAs (miRNAs) are single-stranded and noncoding RNA molecules that control post-transcriptional gene regulation. miRNAs can be tumor suppressors or oncogenes through various mechanism including cancer cel...

Authors: Masashi Ishikawa, Masae Iwasaki, Atsuhiro Sakamoto and Daqing Ma

Effectiveness of securing central venous catheters with topical tissue adhesive in patients undergoing cardiac surgery: a randomized controlled pilot study

Central venous catheters (CVCs) play an important role during cardiac surgery. Topical tissue adhesives form a thin film of coating that becomes bound to keratin in the epidermis. The advantage of this “super ...

Authors: Naruemol Prachanpanich, Sunthiti Morakul and Napanont Kiatmongkolkul

Use of volume controlled vs. pressure controlled volume guaranteed ventilation in elderly patients undergoing laparoscopic surgery with laryngeal mask airway

The peak inspiratory pressure (PIP) is crucial in mechanical ventilation with supraglottic airway device (SAD). Pressure-controlled ventilation volume-guaranteed (PCV-VG), delivering a preset tidal volume with...

Authors: Ping Wang, Shihao Zhao, Zongbin Gao, Jun Hu, Yao Lu and Jinbao Chen

General versus regional anaesthesia for caesarean section indicated for acute foetal distress: a retrospective cohort study

Acute foetal distress (AFD) is a life-threatening foetal condition complicating 2% of all pregnancies and accounting for 8.9% of caesarean sections (CS) especially in developing nations. Despite the severity o...

Authors: Junette Arlette Mbengono Metogo, Theophile Njamen Nana, Brian Ajong Ngongheh, Emelinda Berinyuy Nyuydzefon, Christoph Akazong Adjahoung, Joel Noutakdie Tochie and Jacqueline Ze Minkande

Impact of goal-directed hemodynamic management on the incidence of acute kidney injury in patients undergoing partial nephrectomy: a pilot randomized controlled trial

The incidence of acute kidney injury (AKI) remains high after partial nephrectomy. Ischemia-reperfusion injury produced by renal hilum clamping during surgery might have contributed to the development of AKI. ...

Authors: Qiong-Fang Wu, Hao Kong, Zhen-Zhen Xu, Huai-Jin Li, Dong-Liang Mu and Dong-Xin Wang

Heart rate variability-derived features based on deep neural network for distinguishing different anaesthesia states

Estimating the depth of anaesthesia (DoA) is critical in modern anaesthetic practice. Multiple DoA monitors based on electroencephalograms (EEGs) have been widely used for DoA monitoring; however, these monito...

Authors: Jian Zhan, Zhuo-xi Wu, Zhen-xin Duan, Gui-ying Yang, Zhi-yong Du, Xiao-hang Bao and Hong Li

High frequency jet ventilation through mask contributes to oxygen therapy among patients undergoing bronchoscopic intervention under deep sedation

High frequency jet ventilation (HFJV) is an open ventilating technique to maintain ventilation for emergency or difficult airway. However, whether jet ventilation or conventional oxygen therapy (COT) is more e...

Authors: Mingyuan Yang, Bin Wang, Qingwu Hou, Yunzhi Zhou, Na Li, Hongwu Wang, Lei Li and Qinghao Cheng

Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors

Few studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors.

Authors: Clément Medrinal, Guillaume Prieur, Tristan Bonnevie, Francis-Edouard Gravier, Denys Mayard, Emmanuelle Desmalles, Pauline Smondack, Bouchra Lamia, Yann Combret and Guillaume Fossat

Effects of dexmedetomidine on intraoperative hemodynamics, recovery profile and postoperative pain in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial

To investigate the optimal dose of dexmedetomidine to maintain hemodynamic stability, prevent of cough and minimize postoperative pain for patients undergoing laparoscopic cholecystectomy.

Authors: Qin Ye, Fangjun Wang, Hongchun Xu, Le Wu and Xiaopei Gao

Actual versus ideal body weight dosing of sugammadex in morbidly obese patients offers faster reversal of rocuronium- or vecuronium-induced deep or moderate neuromuscular block: a randomized clinical trial

This randomized, double-blind trial evaluated sugammadex-mediated recovery time from rocuronium- or vecuronium-induced moderate (M-) or deep (D-) neuromuscular block in morbidly obese adults dosed by actual (A...

Authors: Jay C. Horrow, Wen Li, Manfred Blobner, John Lombard, Marcel Speek, Matthew DeAngelis and W. Joseph Herring

A gap existed between physicians’ perceptions and performance of pain, agitation-sedation and delirium assessments in Chinese intensive care units

Pain, agitation-sedation and delirium management are crucial elements in the care of critically ill patients. In the present study, we aimed to present the current practice of pain, agitation-sedation and deli...

Authors: Kai Chen, Yan-Lin Yang, Hong-Liang Li, Dan Xiao, Yang Wang, Linlin Zhang and Jian-Xin Zhou

General anaesthesia related mortality in a limited resource settings region: a retrospective study in two teaching hospitals of Butembo

General anaesthesia (GA) in developing countries is still a high-risk practice, especially in Africa, accompanied with high morbidity and mortality. No study has yet been conducted in Butembo in the Democratic...

Authors: Furaha Nzanzu Blaise Pascal, Agnes Malisawa, Andreas Barratt-Due, Felix Namboya and Gregor Pollach

Analgesic efficacy and safety of erector spinae plane block in breast cancer surgery: a systematic review and meta-analysis

Surgical resection is considered to be the primary and most effective therapy for breast cancer, postoperative pain is an issue gaining significant attention. In recent years, erector spinae plane block (ESPB)...

Authors: Ying Zhang, Tieshuai Liu, Youfa Zhou, Yijin Yu and Gang Chen

Spinal anaesthesia with Chloroprocaine HCl 1% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients

This prospective, randomised, observer-blinded study has been conducted in patients undergoing procedures of the lower extremities to evaluate the time to complete block resolution of 2-chloroprocaine 1% at th...

Authors: Daniela Ghisi, Giorgia Boschetto, Alessandra Maria Spinelli, Sandra Giannone, Jacopo Frugiuele, Marcello Ciccarello and Stefano Bonarelli

Anaesthesia challenges of a parturient with paramyotonia congenita and terminal filum lipoma presenting for labour and caesarean section under epidural anaesthesia – a case report

Paramyotonia congenita is a rare autosomal dominant myopathy which presents with periodic weakness due to cold and exercise. It is caused by mutations of the SCN4 gene which encodes the sodium channel in skele...

Authors: Wei Shyan Siow and Wan-Ling Alyssa Chiew

Left ventricular-arterial coupling as a predictor of stroke volume response to norepinephrine in septic shock – a prospective cohort study

Left ventricular-arterial coupling (VAC), defined as the ratio of arterial elastance (Ea) to left ventricular end-systolic elastance (Ees), is a key determinant of cardiovascular performance. This study aims t...

Authors: Xiaoyang Zhou, Jianneng Pan, Yang Wang, Hua Wang, Zhaojun Xu and Weibo Zhuo

Economic impact of improving patient safety using Sugammadex for routine reversal of neuromuscular blockade in Spain

Neuromuscular blocking (NMB) agents are often administered to facilitate tracheal intubation and prevent patient movement during surgical procedures requiring the use of general anesthetics. Incomplete reversa...

Authors: J. Martinez-Ubieto, C. Aragón- Benedí, J. de Pedro, L. Cea-Calvo, A. Morell, Y. Jiang, S. Cedillo, P. Ramírez-Boix and A. M. Pascual-Bellosta

The visually estimated blood volume in scaled canisters based on a simulation study

The most common technique used worldwide to quantify blood loss during an operation is the visual assessment by the attending intervention team. In every operating room you will find scaled suction canisters t...

Authors: Lara Gerdessen, Vanessa Neef, Florian J. Raimann, Kai Zacharowski and Florian Piekarski

A prospective observational cohort pilot study of the association between midazolam use and delirium in elderly endoscopy patients

Midazolam is a benzodiazepine commonly used in procedural sedation and general anaesthesia. Current anaesthetic guidelines advise the avoidance of benzodiazepines in elderly patients due to concerns of an incr...

Authors: Dickson Lee, Fiona Petersen, Maurice Wu, Gwenda Chapman, Melanie Hayman, Kerrilyn Tomkins and Jeremy Fernando

Does a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone: a systematic review and meta-analysis

In anesthesia, additive drug interactions are used for reducing dose and dose-dependent side-effects. The combination of propofol with volatile anesthetics is rather unusual but might have advantages compared ...

Authors: Alexander Wolf, Helene Selpien, Helge Haberl and Matthias Unterberg

Safety of percutaneous dilatational tracheotomy (PDT) with the rigid tracheotomy endoscope (TED): a 6-month follow-up multicenter investigation

The rigid tracheotomy endoscope (TED) was recently introduced to improve the fiberoptic technique during percutaneous dilatational tracheotomy (PDT) in critically ill patients. The aim was to evaluate the long...

Authors: Andreas Nowak, Eckart Klemm, Caroline Michaelsen, Taras I. Usichenko and Sven Koscielny

Comparative study of analgesia nociception index (ANI) vs. standard pharmacokinetic pattern for guiding intraoperative fentanyl administration among mastectomy patients

The Analgesia Nociception Index (ANI) has been suggested as a non-invasive guide for analgesia. Our objective was to compare the efficacy of ANI vs. standard pharmacokinetic pattern for guiding intraoperative ...

Authors: Sirirat Tribuddharat, Thepakorn Sathitkarnmanee, Pornlada Sukhong, Maneerat Thananun, Parinda Promkhote and Duangthida Nonlhaopol

Penehyclidine mitigates postoperative nausea and vomiting and intraoperative oculocardiac reflex in patients undergoing strabismus surgery: a prospective, randomized, double-blind comparison

Postoperative nausea and vomiting (PONV) is one of the most frequent complications following strabismus surgery. Penehyclidine, an anticholinergic agent, is widely used as premedication. This study investigate...

Authors: Jiacheng Sun, Xiaofei Cao, Ting Lu, Nan Li, Xinxu Min and Zhengnian Ding

Preoperative anxiety predicted the incidence of postoperative delirium in patients undergoing total hip arthroplasty: a prospective cohort study

Delirium was characterized with a series of symptoms of a sudden onset of disturbances in attention, a loss in memory loss and defects in other cognitive abilities that were also appeared in the syndrome of an...

Authors: Jun Ma, Chuanyao Li, Wei Zhang, Ling Zhou, Shuhua Shu, Sheng Wang, Di Wang and Xiaoqing Chai

The effect of perineural dexamethasone on rebound pain after ropivacaine single-injection nerve block: a randomized controlled trial

Rebound pain after a single-shot nerve block challenges the real benefit of this technique. We aimed to investigate whether perineural dexamethasone addition decreased the incidence of rebound pain after a sin...

Authors: Jie Fang, Yuncen Shi, Fang Du, Zhanggang Xue, Jing Cang, Changhong Miao and Xiaoguang Zhang

Anesthetic protocol for right ventricular dysfunction management in heart transplantation: systematic review, development and validation

Right Ventricular Dysfunction (RVD) is the most frequent intraoperative hemodynamic complication in Heart Transplantation (HTx). RVD occurs in 0.04–1.0% of cardiac surgeries with cardiotomy and in 20–50% of HT...

Authors: Lucas Nepomuceno Barros, Ricardo Barreira Uchoa, Juan Alberto Cosquillo Mejia, Rogean Rodrigues Nunes, Denise Araujo Silva Nepomuceno Barros and Filadelfo Rodrigues Filho

Ultrasound-guided transmuscular quadratus lumborum block reduced postoperative opioids consumptions in patients after laparoscopic hepatectomy: a three-arm randomized controlled trial

To investigate whether transmuscular quadratus lumborum block (TQLB) combined with oxycodone-based patient-controlled intravenous analgesia (PCIA) compared with sufentanil-based patient-controlled intravenous ...

Authors: Mengya Pang, Guoliang Sun, Weifeng Yao, Shaoli Zhou, Ning Shen, Haofeng Liao, Hanbing Xie, Wanling Gao and Mian Ge

Procedural times in early non-intubated VATS program - a propensity score analysis

Non-intubated video-assisted thoracic surgery (NiVATS) has been introduced to surgical medicine in order to reduce the invasiveness of anesthetic procedures and avoid adverse effects of intubation and one-lung...

Authors: Isabella Metelmann, Johannes Broschewitz, Uta-Carolin Pietsch, Gerald Huschak, Uwe Eichfeld, Sven Bercker and Sebastian Kraemer

Physicians’ perceptions regarding acute bleeding management: an international mixed qualitative quantitative study

Acute bleeding is an omnipresent challenge for all physicians. Uncontrolled hemorrhage is the most common preventable cause of death after trauma worldwide. In different surgical disciplines, hemorrhage repres...

Authors: Tadzio R. Roche, Doreen J. Wetli, Julia Braun, Ezequiel D. Kataife, Federico G. Mileo, Donat R. Spahn, David W. Tscholl and Sadiq Said

Yes- mind the gap!

We totally agree with Deana and Colleagues that missing intermediate care 1) might be an explanation for unexpected unfavorable outcome and 2) strengthening of intermediate care has the potential to lower this...

Authors: Uwe Hamsen, Niklas Drotleff, Rolf Lefering, Julius Gerstmeyer, Thomas Armin Schildhauer and Christian Waydhas

Effects of an individualized analgesia protocol on the need for medical interventions after adenotonsillectomy in children: a randomized controlled trial

It has been proposed that the dose of rescue opioids should be individually titrated to the severity of obstructive sleep apnea after adenotonsillectomy. However, a sleep study is not always available before a...

Authors: Jian Guo, Peijun Zhuang, Kun Liu, Yuanyuan Wan and Xuan Wang

Intensive care unit discharge: mind the gap!

Mortality after intensive care discharge is a hot topic in critical care medicine. Many factors probably play a role: patient’s comorbidities and severity of the disease may have great impact on mortality. How...

Authors: Cristian Deana, Giovanni Sermann and Amato De Monte

The effects of a preoperative multidisciplinary conference on outcomes for high-risk patients with challenging surgical treatment options: a retrospective study

Surgical options for patients vary with age and comorbidities, advances in medical technology and patients’ wishes. This complexity can make it difficult for surgeons to determine appropriate treatment plans i...

Authors: Masayoshi Koike, Mie Yoshimura, Yasushi Mio and Shoichi Uezono

Completeness of the operating room to intensive care unit handover: a matter of time?

Handovers of post-anesthesia patients to the intensive care unit (ICU) are often unstructured and performed under time pressure. Hence, they bear a high risk of poor communication, loss of information and pote...

Authors: Fabian Dusse, Johanna Pütz, Andreas Böhmer, Mark Schieren, Robin Joppich and Frank Wappler

Development and validation of a predictive score for ICU delirium in critically ill patients

The incidence of delirium in intensive care unit (ICU) patients is high and associated with a poor prognosis. We validated the risk factors of delirium to identify relevant early and predictive clinical indica...

Authors: Huijuan Zhang, Jing Yuan, Qun Chen, Yingya Cao, Zhen Wang, Weihua Lu and Juan Bao

Implementing ERAS: how we achieved success within an anesthesia department

The Massachusetts General Hospital is a large, quaternary care institution with 58 operating rooms, 164 anesthesiologists, 76 certified nurse anesthetists (CRNAs), an anesthesiology residency program that admi...

Authors: Dan B. Ellis, Aalok Agarwala, Elena Cavallo, Pam Linov, Michael K. Hidrue, Marcela G. del Carmen and Rachel Sisodia

Clinical outcomes of postoperative extracorporeal membrane oxygenation support in Stanford type a aortic dissection

Extracorporeal membrane oxygenation (ECMO) support may be considered to reduce mortality but survival and clinical outcomes are uncertain after Stanford type A Aortic dissection (TAAD). We analyzed the data of...

Authors: Fudong Fan, Qing Zhou, Jun Pan, Hailong Cao, Kai Li, Yunxing Xue, Min Ge, Xuan Luo, Yang Chen and Dongjin Wang

Frequency of the requirement of inappropriate uncuffed tracheal tube size for pediatric patients: a retrospective observational analysis

The insertion of inappropriately sized uncuffed endotracheal tubes (ETTs) with a tight seal or presence of air leakage may be necessary in children. This study aimed to analyze the frequency of the requirement...

Authors: Hiroshi Hanamoto, Hikaru Nakagawa and Hitoshi Niwa

Comparison of the in-vivo effect of two tranexamic acid doses on fibrinolysis parameters in adults undergoing valvular cardiac surgery with cardiopulmonary bypass - a pilot investigation

The blood saving efficacy of TXA in cardiac surgery has been proved in several studies, but TXA dosing regimens were varied in those studies. Therefore, we performed this study to investigate if there is a dos...

Authors: Zhen-feng Zhou, Wen Zhai, Li-na Yu, Kai Sun, Li-hong Sun, Xiu-fang Xing and Min Yan

Effects of the reservoir bag disconnection on inspired gases during general anesthesia: a simulator-based study

Fresh gas decoupling is a feature of the modern anesthesia workstation, where the fresh gas flow (FGF) is diverted into the reservoir bag and is not added to the delivered tidal volume, which thus remains cons...

Authors: Miljenko Križmarić, Uroš Maver, Marko Zdravković and Dušan Mekiš