Articles

Effects of different plasma target concentrations of remifentanil on the MAC_BAR of sevoflurane in children with laparoscopic surgery

To investigate the effects of different plasma target concentrations of remifentanil on the minimum alveolar concentration (MAC) for blocking adrenergic response (BAR) of sevoflurane in children with laparosco...

Authors: Dan Wang, Juan Xu, Xiao-Lin Yang, Yan-Xia Guo, Ping-Ping Jiang and Guo-Yuan Zhang

Retraction Note: Preoperative versus postoperative ultrasound-guided rectus sheath block for improving pain, sleep quality and cytokine levels in patients with open midline incisions undergoing transabdominal gynecological surgery: a randomized controlled trial

This article has been retracted. Please see the Retraction Notice for more detail: https://​doi.​org/​10.​1186/​s12871-021-01437-z

Authors: Feng Jin, Zhe Li, Wen-fei Tan, Hong Ma, Xiao-qian Li and Huang-wei Lu

Impact of epidural labor analgesia using sufentanil combined with low-concentration ropivacaine on maternal and neonatal outcomes: a retrospective cohort study

Whether epidural administered sufentanil combined with low-concentration ropivacaine affected labor progress as well as maternal and neonatal outcomes still remained unknown. The aim of this study was to asses...

Authors: Le Zhang, Chengjie Xu and Yue Li

Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial

Parathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of reco...

Authors: Shenghong Hu, Teng Shu, Siqi Xu, Xia Ju, Shengbin Wang and Li Ma

The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients: a randomized, double – blind study

Down syndrome (DS) is associated with intellectual disability. DS patients may be unable to cooperate and often require general anesthesia even for minor surgeries. Rapid recovery significantly contributes to ...

Authors: Emmanouil Gkliatis, Alexandros Makris and Chryssoula Staikou

Dexmedetomidine-induced hemodynamic instability in patients undergoing orthopedic upper limb surgery under brachial plexus block: a retrospective study

Hemodynamic instability is a frequent adverse effect following administration of dexmedetomidine (DMED). In this study, we evaluated the incidence of DMED-induced hemodynamic instability and its predictive fac...

Authors: A Ram Doo, Hyungseok Lee, Seon Ju Baek and Jeongwoo Lee

Spinal versus general anesthesia for patients undergoing outpatient total knee arthroplasty: a national propensity matched analysis of early postoperative outcomes

A comparison of different anesthetic techniques to evaluate short term outcomes has yet to be performed for patients undergoing outpatient knee replacements. The aim of this investigation was to compare short ...

Authors: Mark C. Kendall, Alexander D. Cohen, Stephanie Principe-Marrero, Peter Sidhom, Patricia Apruzzese and Gildasio De Oliveira

Neuromuscular block in patients 80 years and older: a prospective, controlled study

An increasing number of patients older than 80 years are undergoing anesthesia, but little information is available regarding pharmacodynamic effects of myorelaxants in this population. This study aims to comp...

Authors: Denis Schmartz, Raouf Sghaier, Paul Bernard, Jean François Fils and Thomas Fuchs-Buder

Influence of rosuvastatin treatment on cerebral inflammation and nitro-oxidative stress in experimental lung injury in pigs

Many patients with acute respiratory distress syndrome (ARDS) suffer from cognitive impairment after hospital discharge. Different mechanisms have been implicated as potential causes for this impairment, inter...

Authors: Jens Kamuf, Andreas Garcia Bardon, Alexander Ziebart, Robert Ruemmler, Johannes Schwab, Mobin Dib, Andreas Daiber, Serge C. Thal and Erik K. Hartmann

Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled trial

Dexmedetomidine promotes normal sleep architecture; the drug also improves analgesia. We therefore tested the hypothesis that supplementing intravenous analgesia with dexmedetomidine reduces delirium in older ...

Authors: Hong Hong, Da-Zhi Zhang, Mo Li, Geng Wang, Sai-Nan Zhu, Yue Zhang, Dong-Xin Wang and Daniel I. Sessler

The relationship between the effect-site concentration of propofol and sedation scale in children: a pharmacodynamic modeling study

Continuous infusion of propofol has been used to achieve sedation in children. However, the relationship between the effect-site concentration (C_e) of propofol and sedation scale has not been previously examined....

Authors: Young-Eun Jang, Sang-Hwan Ji, Ji-Hyun Lee, Eun-Hee Kim, Jin-Tae Kim and Hee-Soo Kim

Optimal angle of needle insertion for spinal anesthesia in patients with spondylolisthesis: an ultrasonographic study

Spondylolisthesis is a common degenerative spinal deformity. At the level of spondylolisthesis, the anatomy of the interlaminar space may differ from normal spine, in which case optimal angle of the needle ins...

Authors: Youngwon Kim, Seokha Yoo, Sun-Kyung Park, Hansu Bae, Young-Jin Lim and Jin-Tae Kim

Association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in the intensive care unit: a secondary analysis of a large prospective observational study

Malnutrition in intensive care unit (ICU) patients is associated with adverse clinical outcomes. The modified nutrition risk in the critically ill score (mNUTRIC) was proposed as an appropriate nutritional ass...

Authors: Na Wang, Mei-Ping Wang, Li Jiang, Bin Du, Bo Zhu and Xiu-Ming Xi

Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study

Circulatory failure frequently occurs after out-of-hospital cardiac arrest (OHCA) and is part of post-cardiac arrest syndrome (PCAS). The aim of this study was to investigate circulatory disturbances in PCAS ...

Authors: Halvor Langeland, Daniel Bergum, Trond Nordseth, Magnus Løberg, Thomas Skaug, Knut Bjørnstad, Ørjan Gundersen, Nils-Kristian Skjærvold and Pål Klepstad

Effects of the addition of dexamethasone on postoperative analgesia after anterior cruciate ligament reconstruction surgery under quadruple nerve blocks

Anterior cruciate ligament (ACL) reconstruction is an invasive surgical procedure for the knee. Quadruple nerve blocks including continuous femoral nerve block and single-injection sciatic, obturator, and late...

Authors: Yuki Aoyama, Shinichi Sakura, Shoko Abe, Erika Uchimura and Yoji Saito

Monochromic light reduces emergence delirium in children undergoing adenotonsillectomy; a double-blind randomized observational study

Emergence delirium (ED) is common in pediatric anesthesia. This dissociative state in which the patient is confused from their surroundings and flailing can be self-injurious and traumatic for parents. Treatme...

Authors: Adam C. Adler, Brian H. Nathanson and Arvind Chandrakantan

Case report: Spinal anesthesia for cesarean section in a parturient with Potocki-Lupski syndrome

Potocki -Lupski syndrome is an uncommon disorder caused by a micro-duplication in chromosome 17p11.2. Variable clinical manifestations bring troubles to the general and neuraxial anesthesia, including mental r...

Authors: Junfeng Li, Jie Bao, Di Zhang and Shuzhen Zhou

Effects of circadian rhythm on Narcotrend index and target-controlled infusion concentration of propofol anesthesia

The effects of circadian rhythms on drug metabolism and efficacy are being increasingly recognized. However, the extent to which they affect general anesthesia remains unclear. This study aims to investigate t...

Authors: Jiang-hua Shen, Min Ye, Qian Chen, Yan Chen, Hai-lin Zhao, Ameena Khan, Bin Yi, Jiao-lin Ning, Kai-zhi Lu and Jian-teng Gu

High flow versus conventional nasal cannula for oxygenation and ventilation maintenance during surgery with intravenous deep sedation by propofol: a randomized controlled study

The dead space washout and provision of some level of positive airway pressure by nasal high-flow (NHF) cannula could improve the efficiency of ventilation, oxygenation and maintenance of the upper airway in p...

Authors: Amorn Vijitpavan and Yanin Kooncharoensuk

Sevoflurane blocks glioma malignant development by upregulating circRELN through circRELN-mediated miR-1290/RORA axis

Sevoflurane (Sev) has been reported to inhibit cancer development, and sevoflurane treatment in cancers is implicated with the deregulation of specific non-coding RNAs (ncRNAs). This study aimed to investigate...

Authors: Xiaofang Kang, Hongxia Li and Zaiwang Zhang

Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas

The mechanism of volatile anesthetics on vascular smooth muscle (VSM) contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was designed to determine the effects of sevofluran...

Authors: Shaozhong Yang, Yu Liu, Shanshan Huang, Feihong Jin and Feng Qi

Prediction of postoperative nausea and vomiting by point-of-care gastric ultrasound: can we improve complications and length of stay in emergency surgery? A cohort study

Postoperative nausea and vomiting and postoperative ileus are common after major digestive surgery and represent one of the significant problems in Acute Care Surgery.

Authors: Valerio Cozza, Lorenzo Barberis, Gaia Altieri, Mario Donatelli, Gabriele Sganga and Antonio La Greca

The expression of kappa-opioid receptor promotes the migration of breast cancer cells in vitro

Opioid receptors are implicated in cell proliferation and cancer migration. However, the effects and underlying mechanisms of opioid receptor κ (OPRK1) in breast cancer remain unknown.

Authors: Huiqing Li, Zhenzhen Ma and Yunlong Lei

General versus general anaesthesia combined with caudal block in laparoscopic-assisted Soave pull-through of Hirschsprung disease: a retrospective study

Caudal block is one of the most preferred regional anesthesia for sub-umbilical region surgeries in the pediatric population. However, few studies are available on caudal block performed in laparoscopic-assist...

Authors: Zhixiong Lin, Yifan Fang, Lei Yan, Yu Lin, Mingkun Liu, Bing Zhang, Yuanbing He, Yong Shen, Dianming Wu and Longxin Zhang

Bronchial rupture following endobronchial blocker placement: a case report of a rare, unfortunate complication

Lung separation may be achieved through the use of double lumen tubes or endobronchial blockers. The use of lung separation techniques carries the risk of airway injuries which range from minor complications l...

Authors: Shuwen Oo, Rachel Hui Xuan Chia, Yue Li, Hari Kumar Sampath, Sophia Bee Leng Ang, Suresh Paranjothy, John Kit Chung Tam and Chang Chuan Melvin Lee

Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be minimized through monitoring of neuromuscular function and reversal of neuromuscu...

Authors: Ákos I. Fábián, Edömér Tassonyi, Vera Csernoch, Marianna Fedor, Tamás Sohajda, Lajos Szente and Béla Fülesdi

Perioperative temperature management: a survey of 6 Asia–Pacific countries

Anesthesia leads to impairments in central and peripheral thermoregulatory responses. Inadvertent perioperative hypothermia is hence a common perioperative complication, and is associated with coagulopathy, in...

Authors: Wenjun Koh, Murali Chakravarthy, Edgard Simon, Raveenthiran Rasiah, Somrat Charuluxananan, Tae-Yop Kim, Sophia T. H. Chew, Anselm Bräuer and Lian Kah Ti

Emergence agitation after intraoperative neurolytic celiac plexus block with alcohol: a case report

Emergence agitation after general anesthesia may cause several undesirable events in the clinic during patient anesthesia recovery, and acute alcohol intoxication, while rare in surgery, is one of the risk fac...

Authors: Huixuan Zhou, Yinbing Pan, Cunming Liu and Xiaodi Sun

Protective effects of dexmedetomidine on cerebral ischemia/reperfusion injury via the microRNA-214/ROCK1/NF-κB axis

Cerebral ischemia/reperfusion injury (CIRI) is a complication of surgical procedure associated with high mortality. The protective effect of dexmedetomidine (DEX) on CIRI has been explored in previous works, y...

Authors: Wenyi Liu, Cuihua Shao, Chuanshan Zang, Jian Sun, Min Xu and Yuna Wang

Anaesthetic management using remimazolam in a patient with severe aortic stenosis: a case report

The administration of general anaesthesia in patients with aortic stenosis (AS) requires careful attention to haemodynamics. We used remimazolam for the induction and maintenance of anaesthesia in a woman with...

Authors: Minako Furuta, Hisakatsu Ito and Mitsuaki Yamazaki

Adequacy of maternal anesthesia depth with two sodium thiopental doses in elective caesarean section: a randomized clinical trial

Administration of an optimal dose of anesthetic agent to ensure adequate depth of hypnosis with the lowest risk of adverse effects to the fetus is highly important in cesarean section. Sodium thiopental (STP) ...

Authors: Golnar Sabetian, Farid Zand, Fatemeh Mirhadi, Mohammad Reza Hadavi, Elham Asadpour, Laleh Dehghanpisheh, Zeinabsadat Fattahi Saravi and Seyed Mostajab Razavi

Hemodynamic, renal and hormonal effects of lung protective ventilation during robot-assisted radical prostatectomy, analysis of secondary outcomes from a randomized controlled trial

Lung protective ventilation with low tidal volume (TV) and increased positive end-expiratory pressure (PEEP) can have unfavorable effects on the cardiovascular system. We aimed to investigate whether lung prot...

Authors: Sidse Høyer, Frank H. Mose, Peter Ekeløf, Jørgen B. Jensen and Jesper N. Bech

Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial

A few studies have reported that administration of lidocaine and dexmedetomidine relieves the incidence of postoperative nausea and vomiting (PONV). We explored whether combined infusion of lidocaine plus dexm...

Authors: Siqi Xu, Shengbin Wang, Shenghong Hu, Xia Ju, Qing Li and Yuanhai Li

Head-neck movement may predispose to the development of arytenoid dislocation in the intubated patient: a 5-year retrospective single-center study

Arytenoid dislocation is a rare laryngeal injury that may follow endotracheal intubation. We aimed to determine the incidence and risk factors for arytenoid dislocation after surgery under general anaesthesia.

Authors: Eun-A Jang, Kyung Yeon Yoo, Seongheon Lee, Seung Won Song, Eugene Jung, Joungmin Kim and Hong-Beom Bae

Pharmacokinetics and safety of liposomal bupivacaine after local infiltration in healthy Chinese adults: a phase 1 study

Liposomal bupivacaine (LB) is a long-acting formulation of bupivacaine. The safety and efficacy of LB has been demonstrated across surgical procedures. However, pharmacokinetic (PK) parameters and safety of LB...

Authors: Bernard MY Cheung, Pauline Yeung Ng, Ying Liu, Manman Zhou, Vincent Yu, Julia Yang and Natalie Q. Wang

Design of a novel multifunction decision support/alerting system for in-patient acute care, ICU and floor (AlertWatch AC)

Multifunction surveillance alerting systems have been found to be beneficial for the operating room and labor and delivery. This paper describes a similar system developed for in-hospital acute care environmen...

Authors: Douglas A. Colquhoun, Ryan P. Davis, Theodore T. Tremper, Jenny J. Mace, Jan M. Gombert, William D. Sheldon, Joseph J. Connolly, Justin F. Adams and Kevin K. Tremper

Comparison of laryngeal mask airway and endotracheal tube in preterm neonates receiving general anesthesia for inguinal hernia surgery: a retrospective study

Preterm neonates are at higher risk of developing inguinal hernia, and have an increased risk of perioperative adverse events. Laryngeal mask airway (LMA) is claimed to be associated to decreasing perioperativ...

Authors: Miao-Pei Su, Ping-Yang Hu, Jao-Yu Lin, Shu-Ting Yang, Kuang-I Cheng and Chia-Heng Lin

Oxycodone versus morphine for analgesia after laparoscopic endometriosis resection

The objective of this study was to compare the analgesic potency of oxycodone versus morphine after laparoscopic deep infiltrating endometriosis resection.

Authors: Lijun Niu, Lihong Chen, Yanhua Luo, Wenkao Huang and Yunsheng Li

Risk factors and predictive value of perioperative neurocognitive disorders in elderly patients with gastrointestinal tumors

This study aims to investigate the risk factors of perioperative neurocognitive disorders (PNDs) mainly including postoperative cognitive dysfunction (POCD) in elderly patients with gastrointestinal tumors, an...

Authors: Yong-Li Li, Hui-Fan Huang and Yuan Le

Effectiveness of analgesia with hydromorphone hydrochloride for postoperative pain following surgical repair of structural congenital malformations in children: a randomized controlled trial

Effective postoperative analgesia is needed to prevent the negative effects of postoperative pain on patient outcomes. To compare the effectiveness of hydromorphone hydrochloride and sufentanil, combined with ...

Authors: Yongying Pan, Yimin Wang, Dongxu Lie, Di Liu, Xi Chen, Zeyan Wu, Liumei Chen, Huaizhen Wang, Liangming Peng, Huiying Liang, Xingrong Song and Baisong Zhao

Correction to: Cut-off points between pain intensities of the postoperative pain using receiver operating characteristic (ROC) curves

Authors: Sooyoung Cho, Youn Jin Kim, Minjin Lee, Jae Hee Woo and Hyun Jung Lee

Impaired vascular endothelial function as a perioperative risk predictor – a prospective observational trial

In the recent years, an increasing number of patients with multiple comorbidities (e.g. coronary artery disease, diabetes, hypertension) presents to the operating room. The clinical risk factors are accompanie...

Authors: Volker Schick, Marc Boensch, Milan van Edig, Jonas Alfitian, Tülay Pola, Hannes Ecker, Falko Lindacher, Kija Shah-Hosseini, Wolfgang A. Wetsch, Bernhard Riedel and Robert Schier

Comparison of accuracy of two uncalibrated pulse contour cardiac output monitors in off-pump coronary artery bypass surgery patients using pulmonary artery catheter-thermodilution as a reference

Cardiac output (CO) is a key measure of adequacy of organ and tissue perfusion, especially in critically ill or complex surgical patients. CO monitoring technology continues to evolve. Recently developed CO mo...

Authors: Ramakrishna Mukkamala, Benjamin A. Kohl and Aman Mahajan

Postoperative pain treatment with transmuscular quadratus lumborum block and fascia iliaca compartment block in patients undergoing total hip arthroplasty: a randomized controlled trial

Patients often suffer moderate or even severe pain after total hip arthroplasty; such pain seriously affects early postoperative recovery. This study aimed to investigate the analgesic efficacy of ultrasound-g...

Authors: Qin Xia, Wenping Ding, Chao Lin, Jiayi Xia, Yahui Xu and Mengxing Jia

The effects of shoulder arthroscopy on ultrasound image quality of the interscalene brachial plexus: a pre-procedure vs post-procedure comparative study

Fluid extravasation from the shoulder compartment and subsequent absorption into adjacent soft tissue is a well-documented phenomenon in arthroscopic shoulder surgery. We aimed to determine if a qualitative di...

Authors: Jason K. Panchamia, Ram Jagannathan, Bridget P. Pulos, Adam W. Amundson, Joaquin Sanchez-Sotelo, David P. Martin and Hugh M. Smith

Hundred most cited articles in perioperative neurocognitive disorder: a bibliometric analysis

In line with aging populations and increased application of anesthesia and surgery, perioperative neurocognitive disorder (PND) has received growing attention worldwide. Considerable researches into PND are be...

Authors: Xinning Mi, Xiaoxiao Wang, Ning Yang, Yongzheng Han, Yue Li, Taotao Liu, Dengyang Han, Yi Yuan, Yiyun Cao, Chengmei Shi, Xiangyang Guo, Yang Zhou and Zhengqian Li

Effects of different vasopressors on the contraction of the superior mesenteric artery and uterine artery in rats during late pregnancy

Hypotension after neuraxial anaesthesia is one of the most common complications during caesarean section. Vasopressors are the most effective method to improve hypotension, but which of these drugs is best for...

Authors: Tingting Wang, Limei Liao, Xiaohui Tang, Bin Li and Shaoqiang Huang

Intraoperative protective ventilation in patients undergoing major neurosurgical interventions: a randomized clinical trial

Post-operative pulmonary complications (PPC) can develop in up to 13% of patients undergoing neurosurgical procedures and may adversely affect clinical outcome. The use of intraoperative lung protective ventil...

Authors: Federico Longhini, Laura Pasin, Claudia Montagnini, Petra Konrad, Andrea Bruni, Eugenio Garofalo, Paolo Murabito, Corrado Pelaia, Valentina Rondi, Fabrizio Dellapiazza, Gianmaria Cammarota, Rosanna Vaschetto, Marcus J. Schultz and Paolo Navalesi

Analysis of urgent/emergent conversions from monitored anesthesia care to general anesthesia with airway instrumentation

Monitored Anesthesia Care (MAC) is an anesthetic service involving the titration of sedatives/analgesics to achieve varying levels of sedation while avoiding general anesthesia (GA) and airway instrumentation....

Authors: Sang Kim, Brian A. Chang, Amreen Rahman, Hung-Mo Lin, Samuel DeMaria Jr, Jeron Zerillo and David B. Wax

Lung ultrasound predicts clinical course but not outcome in COVID-19 ICU patients: a retrospective single-center analysis

Point-of-care lung ultrasound (LU) is an established tool in the first assessment of patients with coronavirus disease (COVID-19). Purpose of this study was to evaluate the value of lung ultrasound in COVID-19...

Authors: Stephanie-Susanne Stecher, Sofia Anton, Alessia Fraccaroli, Jeremias Götschke, Hans Joachim Stemmler and Michaela Barnikel