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Table 1 Baseline patient characteristics and surgical data

From: A pre-anesthetic bolus of ketamine versus dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing emergency surgery: a randomized, double-blinded, placebo-controlled study

 

Placebo group

(n = 20)

Dexmedetomidine group

(n = 20)

Ketamine group

(n = 20)

P-value

 

Age/year

69.41 ± 4.7

70.01 ± 3.8

71.15 ± 3.9

= 0.371

 

P-value

I vs. II = 0.247

II vs. III = 0.910

I vs. III = 0.205

 

Sex

   

= 0.262

 

 Female

8 (40%)

5 (25%)

10 50%)

 

 Male

12 (60%)

15 (75%)

10 (50%)

 

BMI (kg/m2)

26.91 ± 2.8

25.96 ± 2.2

27.09 ± 2.1

= 0.278

P-value

I vs. II = 0.211

II vs. III = 0.137

I vs. III = 0.810

ASA

    

 I

17 (85%)

16 (80%)

14 (70%)

= 0.503

 II

3 (15%)

4 (20%)

6 (30%)

 

Type of surgery

   

= 0.884

 

 Orthopaedic

8 (40%)

4 (20%)

5 (25%)

 

 Plastic

1 (5%)

1 (5%)

1 (5%)

 

 Urologic

2 (10%)

3 (15%)

2 (10%)

 

 Gastrointestinal

9 (45%)

12 (60%)

12 (60%)

 

Length of surgery (min.)

95.40 ± 20.1

95.01 ± 18.4

69.01 ± 16.3

< 0.001

 

 P-value

I vs. II = 0.946

II vs. III < 0.001

I vs. III < 0.001

 

Anesthesia duration (min.)

121.75 ± 19.5

121.70 ± 20.4

90.75 ± 18.2

< 0.001

 

 P-value

I vs. II = 0.994

II vs. III < 0.001

I vs. III < 0.001

 

Extubation time (min.)

14.25 ± 2.7

12.80 ± 3.4

10.10 ± 2.8

< 0.001

 

 P-value

I vs. II = 0.130

II vs. III = 0.006

I vs. III < 0.001

 

Total fentanyl dose during operation (µg)

   
 

85.01 ± 17.8

81.25 ± 14.5

86.25 ± 17.2

= 0.813

 

 P-value

I vs. II = 0.644

II vs. III = 0.538

I vs. III = 0.878

 
  1. ASA, American Society of Anesthesiologists, BMI; Body Mass Index