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Table 4 Comparison between bolus mode and continuous infusion.

From: Micro- and macrocirculatory effects of norepinephrine on anaesthesia-induced hypotension: a prospective preliminary study

 

BOLUS

CONTINUOUS INFUSION

p

MACROCIRCULATION

 MAP (mmHg)

+21 (15 ; 30)

+ 16 (9 ;26)

0,07

 HR (/min)

- 8 (-12 ; -6)

- 7 (-10 ; -4)

0,2

 CO (L/min)

- 1,5 L (-1,1 ; -2,4)

- 0,9 ( -1,5 ; -0,2)

< 0,001

 SV (mL)

-11 (-8 ; -20)

- 7 (-13 ; -3)

0,009

 GALA (°)

+ 12 (6-15)

+ 7 (3-12)

0,04

MICROCIRCULATION

 PHOTOPLETHYSMOGRAPHY

 PI (finger)(%)

-12 (-24 ; 0)

+ 12 (4-20)

0,008

VIDEOCAPILLAROSCOPY

 MFI

-0,1 (-0,24 ; -0,06)

+0,3 (0,1-0,4)

0,03

 TVD (mm2/mm2)

-0,2 (-0,2-0,7)

+ 2,3 (1,5-3,2)

0,002

 PVD (mm2/mm2)

-0,36 (-1,5 ; -0,8)

+1,44 (-0,7 ; +3)

0,01

 HI (%)

-0.24 (-0,2 ; 0,36)

+0.04 (-0,49 ; 0,25)

0,08

  1. MAP Mean arterial pressure, HR Heart rate, CO Cardiac output, SV Stroke volume, GALA Global afterload angle, TPU Tissue perfusion unit, PI Perfusion index, MFI Microvascular flow index, PPV percentage of perfused vessels, TVD Total vessel density, PVD Perfused vessel density, HI heterogeneity index
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BMC Anesthesiology

ISSN: 1471-2253

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