Skip to main content

Table 3 Continuous infusion parameters evolution over time

From: Micro- and macrocirculatory effects of norepinephrine on anaesthesia-induced hypotension: a prospective preliminary study

 

Baseline

T15’

T30’

T45’

T60’

T180’

T300’

MACROCIRCULATION

 MAP (mmHg)

66 (60-74)

69 (58-78)

68 (58-77)

69 (58-78)

70 (59-80)

79 (76-98)*

83 (77-98)*

 HR (/min)

61 (55-72)

61 (54-73)

61 (55-73)

60 (55-72)

59 (54-68)

58 (55-64)*

57 (55-61)*

 CO (L/min)

4,2 (2,9-6)

4,2 (3-5,8)

4,1 (2,9-5,7)

4,1 (3,1-5)

4,1 (3-4,5)

3,8(3-5,8)*

3,9 (3-5,6)*

 SV (mL)

64 (46-81)

64 (46-80)

64 (45-78)

65 (46-82)

64 (43-68)

62 (45-74)

61 (44-76)

 GALA (°)

40 (35-69)

     

43 (37-59)

MICROCIRCULATION

LASER DOPPLER

  TPU

7,1 (1,8-13,4)

7,2 (1,9-13,4)

7,2 (1,9-13,4)

7,0 (1,9-14,3)

7 (2,1-14,7)

7,1 (4,4-14)

7,1 (4,5-12,6)

PHOTOPLETHYSMOGRAPHY

  PI (finger) (%)

5,5 (3,2-8,3)

5,3 (2,1-7,8)

5,2 (2,1-7,8)

5,1 (2-8,1)

5 (2,2-8,3)

5,9 (3-8,3)

6,4 (3,3-8)

  PI (ear) (%)

1,4 (0,6-1,9)

1,4 (0,6-1,9)

1,4 (0,6-1,9)

1,4 (0,6-1,8)

1,4 (0,7-1,9)

1,8 (0,8-2,1)

1,8 (0,8-2,1)

NIRS

  StO2 (%)

87 (82-90)

88 (83-90)

88 (82-89)

88 (82-89)

88 (84-89)

85 (82-89)

85 (82-89) *

  THI (%)

12,6 (10,5-14,1)

12,4 (10,6-14,1)

12,4 (10,6-14)

12,5 (10,5-14)

12,4 (10,4-13,8)

12,1 (9,5-13,3)

12,5 (9,9-13,8)

TISSULAR CO2 (mmHg)

40 (34-43)

39 (34-43)

40 (34-43)

40 (34-43)

40 (34-43)

39 (33-43)

39 (33-43)

VIDEOCAPILLAROSCOPY

  MFI

1,8 (1,7-2)

     

2,1 (1,8-2,4)

  PPV (%)

71,6 (61,2-76,7)

     

69,4 (60,1-74,6)

  TVD (mm2/mm2)

15,1 (14,1-15,5)

     

17,4 (15,6-18,7) *

  PVD (mm2/mm2)

10,1 (9-11,5)

     

11,8* (10,7-13,1)

  HI

0,66 (0,4-1)

     

0,44 (0,36-0,8)

  1. Data are expressed in median (IQR). MAP Mean arterial pressure, HR Heart rate, CO Cardiac output, SV Stroke volume, GALA Global afterload angle, TPU Tissue perfusion unit, PI Perfusion index, MFI Microvascular flow index, PPV Percentage of perfused vessels, StO2 Tissular saturation in O2, THI Tissular hemoglobin index, TVD Total vessel density, PVD Perfused vessel density, HI Heterogeneity Index. (*) = p < 0,05