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Correction to: Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy

The Original Article was published on 22 January 2016

Correction

Following publication of the original article [1], the authors reported that additional file 10 contained a typing error in the table “Percentage of responders (≥50% max TOTPAR) over two, four, six and eight hours (single-dose phase) (ITT Population)”. The table is to be read as follows:

  DKP/TRAM(N = 152) DKP (N = 151) TRAM (N = 150) Placebo (N = 153)
TOTPAR2 Responder, n (%) 91 (60) 69 (46) 58 (39) 50 (33)
Non-Responder, n (%) 60 (40) 82 (54) 91 (61) 103 (67)
Treatment comparisons p-value
DKP/TRAM vs. DKP 0.011
DKP/TRAM vs. TRAM <0.001
DKP vs. Placebo 0.020
TRAM vs. Placebo 0.258
TOTPAR4 Responder, n (%) 99 (65) 80 (53) 65 (43) 49 (32)
Non-Responder, n (%) 52 (34) 71 (47) 84 (56) 104 (68)
Treatment comparisons p-value
DKP/TRAM vs. DKP 0.026
DKP/TRAM vs. TRAM <0.001
DKP vs. Placebo <0.001
TRAM vs. Placebo 0.038
TOTPAR6 Responder, n (%) 105 (69) 72 (48) 64 (43) 49 (32)
Non-Responder, n (%) 46 (30) 79 (52) 85 (57) 104 (68)
Treatment comparisons p-value
DKP/TRAM vs. DKP <0.001
DKP/TRAM vs. TRAM <0.001
DKP vs. Placebo 0.005
TRAM vs. Placebo 0.050
TOTPAR8 Responder, n (%) 100 (66) 72 (48) 66 (44) 47 (31)
Non-Responder, n (%) 51 (34) 79 (52) 83 (55) 106 (69)
Treatment comparisons p-value
DKP/TRAM vs. DKP 0.001
DKP/TRAM vs. TRAM <0.001
DKP vs. Placebo 0.002
TRAM vs. Placebo 0.015

TOTPAR: total pain relief; % max TOTPAR: percentage of the theoretical maximum possible TOTPAR; ITT: intention-to-treat; DKP/TRAM: dexketoprofen trometamol/tramadol hydrochloride 25 mg/75 mg; DKP: dexketoprofen trometamol 25 mg; TRAM: tramadol hydrochloride 100 mg; N: number of patients; n: number of patients with data. The ITT population included all patients randomised; response was defined as the achievement of at least 50% of the maximum possible TOTPAR within the respective treatment arm; TOTPAR was calculated as the time-weighted sum of the pain relief (PAR) scores; PAR was measured on a five-point verbal rating scale (VRS) (0 = none, 1 = slight, 2 = moderate, 3 = good, 4 = complete); the percentage of PAR responders was analysed using a chi-square test.

Reference

  1. 1.

    Moore RA, McQuay HJ, Tomaszewski J, Raba G, Tutunaru D, Lietuviete N, Galad J, Hagymasy L, Melka D, Kotarski J, Rechberger T, Fülesdi B, Nizzardo A, Guerrero-Bayón C, Cuadripani S, Pizà-Vallespir B, Bertolotti M. Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy. BMC Anesthesiol. 2016;16:9. https://doi.org/10.1186/s12871-016-0174-5.

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Correspondence to R. A. Moore.

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The online version of the original article can be found under doi:10.1186/s12871-017-0452-x

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Moore, R.A., McQuay, H.J., Tomaszewski, J. et al. Correction to: Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy. BMC Anesthesiol 17, 159 (2017). https://doi.org/10.1186/s12871-017-0452-x

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