Table 1 Patients' demographic data and preoperative condition. Data are presented for all 84 patients that were included in the study, and separately for those patients receiving clonidine and those without oral clonidine premedication. Values are expressed as mean ± standard deviation, median (25th–75th percentile), or n = (%).
From: Factors influencing preoperative stress response in coronary artery bypass graft patients
All patients | Patients with clonidine morning premedication | Patients without clonidine morning premedication | |
|---|---|---|---|
n = 84 | n = 42 | n = 42 | |
Age (years) | 66 ± 9 | 65 ± 9 | 67 ± 8 |
Bodyweight (kg) | 82 ± 10 | 82 ± 11 | 82 ± 10 |
Height (cm) | 173 ± 6 | 173 ± 6 | 173 ± 5 |
BMI (kg · m-2) | 27.3 ± 3.1 | 27.3 ± 3.2 | 27.4 ± 3.0 |
EF (%) | 62 ± 14 | 61 ± 13 | 63 ± 16 |
Affected vessels (n = / %) | |||
n = 1 | 3 (4%) | 0 (0%) | 3 (7%) |
n = 2 | 16 (19%) | 9 (21%) | 7 (17%) |
n = 3 | 64 (76%) | 33 (79%) | 31 (74%) |
n = 4 | 1 (1%) | 0 (0%) | 1 (2%) |
Pre-treated with (n= / %) | |||
ace-inhibitors | 43 (51%) | 17 (40%) | 26 (62%) |
Beta-blockers | 55 (65%) | 26 (62%) | 29 (69%) |
Calcium-antagonists | 12 (14%) | 5 (12%) | 7 (17%) |
Clonidine dose (n= / %) | |||
75 μg | 8 (19%) | ||
150 μg | n/a | 33 (79%) | n/a |
300 μg | 1 (2%) | ||
Time from morning premedication until observational period (hours) | 1.0 (0.5–4.5) | 2.5 (0.5–5.0) | 1.0 (0.5–4.5) |
Heart rate [bpm] | 66 ± 11 | 66 ± 10 | 66 ± 12 |
Mean arterial blood pressure [mmHg] | 102 ± 16 | 100 ± 15 | 104 ± 17 |
Pressure rate product [mmHg·bpm] | 6750 ± 1640 | 6660 ± 1600 | 6850 ± 1690 |
Plasma norepinephrine level (nmol·l-1) | 1.00 ± 0.82 | 0.75 ± 0.48 | 1.26 ± 1.00 |