Table 3 Intra & postoperative data by center

Hydromorphone (mg), H24:

 Center 1

 Center 2

 Center 1 & 2

9.0 (4.9)

5.7 (2.7)

7.6 (4.4)

9.3 (4.8)

6.6 (2.8)

8.1 (4.2)

-0.3 (-4 to 3.4)

-0.9 (-3.3 to 1.6)

-0.3 (-2.8 to 2.1)

0.88^b

0.47^b

0.77^d

Preoperative QoR-15:

 Center 1

 Center 2

 Center 1 & 2

134 (10)

134 (11)

134 (10)

135 (11)

130 (18)

133 (14)

-1 (-10 to 5)

1 (-8 to 21)

1.4 (-5.5 to 8.3)

0.74^d

0.9^d

0. 68^a

Postoperative QoR-15:

 Center 1

 Center 2

 Center 1 & 2

89 (25)

104 (23)

96 (25)

106 (22)

106 (18)

106 (20)

-17 (-36 to 1)

-2 (-29 to 17)

-11 (-23 to 2)

0.064^b

0.86^b

0.10^b

Delta QoR-15 > 8:

 Center 1, n (%)

 Center 2, n (%)

 Center 1 & 2, n (%)

14 (93)

9 (82)

23 (88)

11 (85)

9 (82)

20 (83)

0.09 (-0.14 to 0.32)

0 (0 to 0)

0.05 (-0.14 to 0.24)

0.896^a

1^a

0.9^a

Delta QoR-15 < 8:

 Center 1, n (%)

 Center 2, n (%)

 Center 1 & 2, n (%)

1 (7)

2 (18)

3 (12)

2 (15)

2 (18)

4 (17)