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Table 2 Factors associated with one-year mortality: univariate and multivariate analysis

From: One-year survival of aneurysmal subarachnoid hemorrhage after airplane transatlantic transfer – a monocenter retrospective study

 

Univariate analysis

(n = 148)

Multivariate analysis (n = 148)

One-year survivors

n = 124

One-year

non-survivors

n = 24

P-valuea

Hazard ratio

(95% confidence interval)

P-valueb

Age, years

53 (45–60)

67 (51–71)

0.006

1.03 (1.00–1.07)

0.045

Gender, Woman, n (%)

76 (61)

14 (58)

0.822

  

Hypertension, n (%)

57 (46)

12 (50)

0.824

  

Characteristics on admission

     

Glasgow Coma Scale

15 (13–15)

12 (8–14)

< 0.001

  

Neurological deficit, n (%)

30 (24)

10 (42)

0.085

  

WFNS grading scale

1 (1–2)

4 (2–4)

< 0.001

1.53 (1.16–2.02)

0.003

Fisher scale

4 (2–4)

4 (3–4)

0.030

  

Complications before securing

     

Acute hydrocephalus, n (%)

34 (27)

15 (63)

0.002

2.34 (0.98–5.58)

0.054

Intracranial hypertension, n (%)

16 (11)

8 (33)

0.029

  

Rebleeding, n (%)

3 (2)

1 (4)

0.511

  

Interventions before transatlantic transfer

     

Mechanical ventilation, n (%)

52 (42)

18 (75)

0.004

  

External ventricular drain, n (%)

47 (38)

16 (67)

0.013

  

Time from bleeding to coiling, days

2 (2–3)

2 (2–3)

0.385

  

Complications during the

flight, n (%)

6 (5)

1 (4)

> 0.999

  
  1. Quantitative variables are described as median [interquartile range] and qualitative variables are described as frequency (percentages)
  2. WFNS, World Federation of Neurological Surgeons
  3. ap values were calculated using Wilcoxon rank-sum test and Fisher’s exact test
  4. bp values were calculated using Cox proportional-hazard model