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Table 3 Kaplan-Meier event rates through 30-day follow-up, use of intravenous diuretics and length of stays

From: Preoperative routine measurement of NT-proBNP predicts postoperative morbidity after non-cardiac surgery with intermediate or high surgical risk: an observational study

 

Total

(n = 199)

NT-proBNP

≤ 450 pg/ml

(n = 129)

NT-proBNP

> 450 pg/ml

(n = 70)

p

Composite Morbidity Endpoint - no. (%)

90 (45.9)

41 (32.4)

49 (70.7)

< 0.001

 Any rehospitalisation - no. (%)

23 (11.9)

11 (8.8)

12 (17.7)

0.056

  Cardiac rehospitalisation - no. (%)

3 (1.6)

0 (0.0)

3 (4.4)

0.018

 Acute decompensated heart failure - no. (%)

19 (9.7)

5 (4.0)

14 (20.1)

< 0.001

 Acute kidney injury - no. (%)

36 (19.4)

10 (8.3)

26 (39.8)

< 0.001

  Stage 1 - no. (%)

26 (14.4)

8 (6.7)

18 (29.8)

< 0.001

  Stage 2 - no. (%)

5 (2.8)

1 (0.8)

4 (6.9)

0.026

  Stage 3 - no. (%)

5 (2.8)

1 (0.9)

4 (6.3)

0.025

 Any bacterial infection - no. (%)

63 (32.1)

31 (24.4)

32 (46.3)

0.001

  Pneumonia - no. (%)

8 (4.6)

2 (1.6)

6 (10.9)

0.011

  Abdominal infection - no. (%)

13 (7.1)

10 (8.1)

3 (4.9)

0.433

  Urinary tract infection - no. (%)

13 (7.8)

6 (5.4)

7 (13.0)

0.089

  Wound infection - no. (%)

8 (4.9)

5 (4.8)

3 (4.5)

0.717

  Other - no. (%)

21 (12.4)

8 (7.1)

13 (22.9)

0.003

Further morbidity measures

 Myocardial infarction - no. (%)

0 (0.0)

0 (0.0)

0 (0.0)

1.0

 Wound healing disturbance - no. (%)

10 (5.2)

5 (4.0)

5 (7.4)

0.312

Mortality - no. (%)

4 (2.0)

1 (0.8)

3 (4.3)

0.094

 Cardiac - no. (%)

1 (0.5)

0 (0.0)

1 (1.5)

0.169

Postoperative diuretics

 Postoperative diuretics [IQR] - mg/d*

0.0 [0.0–1.4]

0.0 [0.0–0.0]

0.10 [0.0–5.9]

< 0.001

Length of stays

 ICU stay [IQR] - d

0.9 [0.0–1.3]

0.8 [0–1.1]

1.1 [0.8–3.5]

< 0.001

 Hospital stay [IQR] - d

10 [6-17]

0.8 [6–13]

15 [8–21]

< 0.001

  1. Abbreviations: ICU = intensive care unit; *daily furosemide equivalent dose