Supraglottic jet oxygenation and ventilation improves oxygenation during endoscopic retrograde cholangiopancreatography: a randomized controlled clinical trial

Table 2 Sedation-related adverse events (SRAEs) and subclinical respiratory depression

	Group N(I) (n = 56)	Group W(II) (n = 56)	Group WS(III) (n = 55)	P-value (I vs. II)	P-value (II vs. III)	P-value (I vs. III)
Subclinical respiratory depression[n(%)]	15(27)	12(21)	3(6)	0.508	0.014	0.002
SRAEs[n(%)]	16(29)	12(21)	2(4)	0.383	0.005	0.000
Hypoxemia	12(21)	11(20)	2(4)	0.815	0.009	0.005
Severe hypoxemia	4(7)	1(2)	0(0)	0.364	1.000	0.118
P_ETCO₂<10mmHg[n(%)]	-	13(23)	4(7)	-	0.020	-
Jaw lift[n(%)]	13(23)	11(20)	2(4)	0.645	0.009	0.003
Mask ventilation[n(%)]	5(9)	5(9)	0(0)	1.000	0.057	0.057
Endotracheal intubation[n(%)]	2(4)	0(0)	0(0)	0.495	-	0.495

Subclinical respiratory depression: SpO₂ = 90–95%, SRAEs: SpO₂ < 90% and the implementation of emergency measures; P_ETCO₂: End-tidal carbon dioxide partial pressure. The χ² test and Fisher’s exact test were used to analyze the incidence rate of SRAEs. The P-value was adjusted to 0.05/3 ≈ 0.017 by Bonferroni adjustment

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