Efficacy of postoperative analgesia with intravenous paracetamol and mannitol injection, combined with thoracic paravertebral nerve block in post video-assisted thoracoscopic surgery pain: a prospective, randomized, double-blind controlled trial

Table 2 Pain scores at rest and coughing in the first 48 h

Outcomes	Group C (n = 40)	Group T (n = 40)	Group TP (n = 38)	P-value
Outcomes	Group C (n = 40)	Group T (n = 40)	Group TP (n = 38)	C vs. T vs. TP	C vs. T	C vs. TP	T vs. TP
Valuation status Resting VAS
1 h	2. 42 ± 0.93	1.85 ± 0.48	1.61 ± 0.55	< 0.001	0.003	< 0.001	0.115
6 h	3.25 ± 1.10	2.38 ± 0.49	2.16 ± 0.82	< 0.001	< 0.001	< 0.001	0.417
12 h	2.73 ± 0.72	2.20 ± 0.65	1.82 ± 0.61	< 0.001	0.002	< 0.001	0.034
24 h	2.42 ± 0.59	2.30 ± 0.52	1.89 ± 0.39	< 0.001	0.683	< 0.001	0.001
48 h	1.88 ± 0.56	1.88 ± 0.61	1.87 ± 0.41	0.998
Cough VAS
1 h	3.75 ± 1.08	2.93 ± 0.47	2.61 ± 0.55	< 0.001	< 0.001	< 0.001	0.022
6 h	4.65 ± 1.23	3.55 ± 0.50	3.16 ± 0.82	< 0.001	< 0.001	< 0.001	0.042
12 h	4.05 ± 0.78	3.33 ± 0.80	2.76 ± 0.71	< 0.001	< 0.001	< 0.001	0.005
24 h	3.80 ± 0.76	3.28 ± 0.51	2.61 ± 0.50	< 0.001	0.002	0.030	< 0.001
48 h	3.13 ± 0.65	3.03 ± 0.70	3.05 ± 0.57	0.772

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