Relationship between blood urea nitrogen to serum albumin ratio and short-term mortality among patients from the surgical intensive care unit: a population-based real-world study

Table 4 Multivariate Cox regression analysis of the association between different B/A levels and all-cause mortality

Variable	Model I			Model II			Model III
Variable	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
30-day mortality
B/A	1.041	1.033–1.049	< 0.001	1.018	1.005–1.031	0.008	1.021	1.008–1.035	0.002
Quintiles
Q1 (< 3.67)	Ref			Ref			Ref
Q2 (3.67–5.52)	1.854	1.351–2.545	< 0.001	1.184	0.857–1.638	0.306	1.189	0.859–1.646	0.296
Q3 (5.52–9.69)	1.963	1.435–2.687	< 0.001	1.038	0.744–1.449	0.826	1.133	0.807–1.590	0.470
Q4 (> 9.69)	3.651	2.734–4.877	< 0.001	1.278	0.891–1.831	0.182	1.508	1.045–2.177	0.028
p for trend			< 0.001			0.322			0.032
90-day mortality
B/A	1.039	1.032–1.046	< 0.001	1.019	1.007–1.030	0.001	1.021	1.009–1.033	< 0.001
Quintiles
Q1 (< 3.67)	Ref			Ref			Ref
Q2 (3.67–5.52)	1.633	1.252–2.129	< 0.001	1.102	0.840–1.447	0.483	1.086	0.827–1.427	0.553
Q3 (5.52–9.69)	1.868	1.442–2.241	< 0.001	1.059	0.802–1.396	0.687	1.104	0.833–1.463	0.493
Q4 (> 9.69)	3.311	2.602–4.211	< 0.001	1.329	0.982–1.799	0.066	1.499	1.100–2.041	0.010
p for trend			< 0.001			0.087			0.006

Model I adjusted for nothing
Model II adjusted for age, SOFA score, WBC, hemoglobin, hematocrit, platelet, creatinine, bicarbonate, glucose, phosphorus, magnesium, chlorine, potassium
Model III adjusted for model II plus MV, ARF, AMI, atrial fibrillation, SAH, cirrhosis, sepsis, CKD, malignancy, peripheral vascular disease, severe liver disease, AKI, paraplegia
HR hazard ratio, 95% CI 95% confidence interval, B/A blood urea nitrogen to serum albumin ratio, SOFA sequential organ failure assessment, WBC white blood cell, MV mechanical ventilation, ARF acute respiratory failure, AMI acute myocardial infarction, SAH subarachnoid hemorrhage, CKD chronic kidney disease, AKI acute kidney injury

ISSN: 1471-2253