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Table 1 Patient and catheter characteristics

From: Macro- and microscopic changes in veins with short-term central venous catheters: an observational autopsy study

Patient characteristics

Patients, n = 12 (100%)

Gender; female, number

7 (58%)

Age (years), median (interquartile range)

70 (63–76)

BMI, median (interquartile range)

26 (22–28)

Length of hospital stay (days), median (interquartile range)

8.5 (4.5–24)

Comorbidities, number

  Cardiovascular disease

9 (75%)

  Diagnosed or suspected malignancy

7 (58%)

  Hypertension

5 (42%)

  Hyperlipidaemia

5 (42%)

  Lung disease (COPD, asbestosis)

4 (33%)

  Smoking

4 (33%)

  Diabetes

3 (25%)

  Cerebrovascular disease

3 (25%)

  Kidney failure (with or without dialysis)

2 (17%)

  Alcoholism

2 (17%)

  Psychiatric disorders (depression, anxiety)

2 (17%)

  Heart failure

1 (8.0%)

  Organ transplantation (kidney and pancreas)

1 (8.0%)

  Obesity

1 (8.0%)

  Previous deep venous thrombosis or pulmonary embolism

0 (0.0%)

Cause of death, number

  Acute myocardial infarction

3 (25%)

  Pneumonia and/or acute respiratory distress syndrome

3 (25%)

  Hypovolaemic shock

2 (17%)

  Multiorgan failure

1 (8.0%)

  Heart failure

1 (8.0%)

  Septic shock

1 (8.0%)

  Intracranial haemorrhage

1 (8.0%)

Patients with another CICC within one year before death, number

0 (0.0%)

Patients with prophylactic enoxaparin, number

11 (92%)

Patients with 75 mg acetylsalicylic acid daily

2 (17%)

Routine coagulation during length of stay, median (interquartile range)

  Platelet count (× 109/L)

269 (146–301)

  Prothrombine time, INR

1.2 (1.0–1.4)

  Acute partial thromboplastin time (s) (normal range 26–33 s)

29 (27–34)

  Fibrinogen (g/L), n = 10

2.8 (1.8–5.4)

Catheter characteristics

Catheters, n = 13 (100%)a

Type of catheter, number

  Non-coated polyurethane central venous catheterb

12 (92%)

  Silicone central haemodialysis catheterc

1 (8.0%)

Catheter length, number

  15 cm

8 (62%)

  20 cm

5 (38%)

Number of catheter lumen, number

  1 (5 French)

1 (8.0%)

  2 (7 and 13.5d French)

3 (23%)

  3 (7 French)

2 (15%)

  5 (9.5 French)

7 (54%)

Insertion site, number

  Internal jugular vein

12 (92%)

  Subclavian vein

1 (8.0%)

Insertion side; right, number

10 (77%)

Number of skin punctures, number

1 [1]

Real time ultrasound guided insertion, number

12 (92%)

Insertion complications, number

0 (0.0%)

Days with catheter, median (interquartile range)

7 (1.8–20)

  1. a Two subjects had multiple centrally inserted central catheters (CICCs) inserted in the same vessel on the same day: one patient with polyurethane CICC and one silicone CICC and one patient with CICC, PA-introducer & VA-ECMO cannula. The latter is not reported in this table as they were inserted at the same day as death
  2. b Nine MeritMedical®, Careflow® and three Arrow® Blue FlexTip® CICCs
  3. c MedComp® Hemo-Cath®
  4. d Haemodialysis catheter