Table 2 Case reports of intraoperative systemic thrombolysis for high-risk PE
Article type | Author | Year | Surgery | Thrombolytic | Outcome |
|---|---|---|---|---|---|
5 case series [25] | L. Scheeren | 1994 | Surgical VT | tPA: 20 to 90 mg | 3 survivals, NNS 2 deaths |
Case report [26] | D. Jackson | 2006 | Liver Transplant | tPA: two 50 mg doses | Survived, NNS |
Case report [27] | M. Wenk | 2011 | Cesarean section | Reteplase: two 10 UI doses | Survival, NNS |
2 Case series [28] | S. Aniskevich | 2015 | Liver Transplant | tPA: 50 mg divided in 10-mg bolus followed by 5-mg increments every 5 min | 1 Death 1 Survival, lower extremity weakness |
Case report [29] | J. Cao | 2015 | Distal femur fracture surgery | tPA: 5 mg initial dose followed by infusion of 45 mg/h | Survival, NNS |
Case report [30] | K. Roy | 2018 | Coronary artery bypass graft | tPA: 10 mg initial bolus followed by infusion of 90 mg/h | Survival, NNS |
Case report [31] | R. Holland | 2020 | Spine surgery | tPA: two 50-mg doses. | Survival, NNS |
Case report [32] | A. Karakosta | 2023 | Cesarean Section | tPA: 15 mg | Survival, NNS |