Table 1 Characteristics of the patients included in the study
First Author | Year | Type of Surgery | Glucocorticoids, Dose | Control | Number of Patients I/C | Age Mean (± SD) or Median (Interquartile Range) I/C | Assessment Methods, Time |
|---|---|---|---|---|---|---|---|
Clemmesen | 2018 | Hip fracture surgery | MET, 125 mg | NS | 59/58 | 79 (± 8) / 81 (± 9) | CAM-S, POD1-3 |
Hauer | 2012 | Cardiac surgery | HYD, 100 mg over 10 min before induction of anesthesia, and 10 mg/h on 24 h (POD1), 5 mg/h on POD2, 3*20 mg on POD3, 3*10 mg on POD4 | NS | 56/55 | 69.3 (± 8.9) / 68.0 (± 8.3) | DSM-IV, POD1 |
Huang | 2023 | Internal fixation surgery for geriatric intertrochanteric fracture | DEX, 10 mg in 30 min before being sent to the operating room | NS | 80/80 | 84.5 (79.0–89.0) / 85.0 (79.8–90.2) | Nu-DESC and MDAS, POD 1–5 |
Kluger | 2021 | Hip fracture surgery | DEX, 20 mg before surgery | NS | 40/39 | 81.4 (± 7.2) / 81.4 (± 8.9) | 4AT, POD1-3 |
Mardani | 2013 | Cardiac surgery | DEX, 8 mg before surgery, 8 mg every 8 h for the first three post-operative days | NS | 43/50 | 64.55 (± 11.10) / 60.04 (± 12.77) | MMSE, PROD and POD1-3 |
Sauër | 2014 | Cardiac surgery | DEX, 1 mg/kg (maximum 100 mg) | NS | 367/370 | 67 (± 12) / 66 (± 12) | CAM-ICU, CAM POD1-4 |
Whitlock | 2015 | Cardiac surgery | MET, 250 mg at anaesthetic induction and 250 mg at initiation of CPB | NS | 3755/3752 | 67.5 (± 13.6) / 67.3 (± 13.8) | CAM, POD3 |
Xiang | 2022 | Gastrointestinal surgery | MET, 2 mg/kg before surgery | NS | 84/84 | 71 (68–74) / 70 (68–73) | CAM, CAM-S, POD1-5 |