Fig. 1From: The ED50 and ED95 of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy: a prospective, double-blinded trialDixon and Massey up-and-down plot line chart. The sequence of patients receiving esketamine in Group E. The quality of analgesia was measured using VAS (from 0 to 10) and was defined as ineffective (VAS score ≥ 3) or effective (VAS score<3)Back to article page