Table 3 Association between anaesthesia-related factors and change in cognitive function as a continuous outcome

Type anaesthesia

-General

-Combined general and neuraxial anaesthesia

2.38土2.89

2.32土3.34

T = 0.124

Duration of anaesthesia

R = -0.075

Agents induction anaesthesia

-Propofol

-Other

2.35土3.13

2.82土2.80

T = -0.488

Agents induction analgesia

-Sufentanil

-Remifentanil

-Other

2.40土3.19

2.63土2.48

0.70土2.41

 F = 0.799

Agents maintenance anaesthesia

-Propofol

-Isoflurane

-Sevoflurane

-Other

2.15土2.68

2.17土4.44

2.57土4.13

4.14土2.35

 F = 1.577

Agents maintenance analgesia

-Sufentanil

-Remifentanil

-Other

2.55土3.17

1.42土3.14

2.34土2.65

 F = 1.494

Additional vasoactive medication received

-Yes

-No

2.28土3.18

3.17土1.94

T = 0.912

Mean BIS

R = 0.059

Mean BIS

->=45

-<45

1.77土3.71

1.82土3.45

T = 0.062

BIS lower 45 time

R = − 0.122

BIS lower 45%

R = -0.100

BIS higher 60 time

R = 0.036

BIS higher 60%

R = 0.092

MAP lower 70 time

R = -0.109

MAP 70 AUC

R = -0.078