Table 2 Patient characteristics and anaesthesia-related factors related to postoperative NCD (outcomes of the univariate and multivariate regression analyses)

Age

1.0 (1.0–1.1)

0.078*

Gender

-Female

-Male

1

1.1 (0.5–2.7)

0.784

GFI

-<= 3

->3

1

1.4 (0.5–3.9)

0.525

MMSE

->26

-<= 26

1

7.1 (2.4–21.3)

< 0.001

1

8.9 (2.8–27.9)

< 0.001

CCS

-<= 2

->2

1

1.1 (0.4-3.0)

0.046*

Highest Postoperative complication (ClavienDindo without delirium and death)

-No complication

-Grade I

-Grade II

-Grade III

-Grade IV

1

0.6 (0.1–4.9)

1.3 (0.4–3.7)

1.2 (0.2–5.8)

9.3 (2.0–43.0)

0.061*

Anaesthesia-related factors

Type anesthesia

-General

-Combined general and neuraxial anaesthesia

1

1.2 (0.5–2.9)

0.685

Duration of anaesthesia

1.003 (1.000-1.005)

0.027

0.013

Agents induction anaesthesia

-Propofol

-Other

1

1.4 (0.6–3.1)

0.435

Agents induction analgesia

-Sufentanil

-Remifentanil

-other

1

0.4 (0-2.9)

0 (0)

0.632

Agents maintenance anaesthesia

-Propofol

-Isoflurane

-Sevoflurane

-Other

1

1.2 (0.2–5.9)

0.6 (0.2–2.3)

0 (0)

0.891

Agents maintenance analgesia

-Sufentanil

-Remifentanil

-Other

1

1.3 (0.4–4.2)

0.4 (0–3.0)

0.561

Additional vasoactive medication received

-No

-Yes

1

1.4 (0.2–11.1)

0.776

Mean BIS

1.0 (0.9–1.1)

0.691

Mean BIS

-<45

->=45

1

0.7 (0.2–2.3)

0.551

BIS < 45 time

1.0 (1.0–1.0)

0.380

BIS < 45%

1.0 (1.0–1.0)

0.803

BIS > 60 time

1.0 (1.0–1.0)

0.729

BIS > 60%

1.0 (0.9-1.0)

0.536

MAP < 70 time

1.0 (1.0–1.0)

0.716

MAP 70 AUC

1.0 (1.0–1.0)

0.886