Table 1 Patient characteristics and anaesthesia-related factors
Patient characteristics | Overall n = 196 | Postoperative NCD n = 23 (11.7%) | No Postoperative NCD n = 173 (88.3%) | P |
|---|---|---|---|---|
Age | 72 ± 6 | 75 ± 7 | 72 ± 6 | 0.145 |
Gender | ||||
-Female -Male | 99 (50.5) 97 (49.5) | 11 (47.8) 12 (52.2) | 88 (50.9) 85 (49.1) | 0.784 |
GFI | ||||
-<= 3 ->3 | 128 (75.7) 41 (24.3) | 14 (70.0) 6 (30.0) | 114 (76.5) 35 (23.5) | 0.580 |
MMSE | ||||
-<= 26 ->26 | 17 (8.7) 179 (91.3) | 7 (30.4) 16 (69.6) | 10 (5.8) 163 (94.2) | 0.001 |
CCS | ||||
-<= 2 ->2 | 57 (29.2) 138 (70.8) | 6 (27.3) 16 (72.7) | 51 (29.5) 122 (70.5) | 0.830 |
Disease stage | ||||
-Benign, I, II -III, IV | 111 (57.2) 83 (42.8) | 18 (78.3) 5 (21.7) | 93 (54.4) 78 (45.6) | 0.030 |
Highest postoperative complication according to Clavien-Dindo (without delirium) | ||||
-No complication -Grade I -Grade II -Grade III -Grade IV | 103 (52.6) 17 (8.7) 50 (25.5) 18 (9.2) 8 (4.1) | 10 (43.5) 1 (4.3) 6 (26.1) 2 (8.7) 4 (17.4) | 93 (53.8) 16 (9.2) 44 (25.4) 16 (9.2) 4 (2.3) | 0.015 |
Anaesthesia-related factors | Â | Â | ||
Type anaesthesia | ||||
-General -Combined general and neuraxial anaesthesia | 93 (47.4) 103 (52.6) | 10 (43.5) 13 (56.5) | 83 (48.0) 90 (52.0) | 0.685 |
Duration of anaesthesia | 203土217 | 280土260 | 195土218 | 0.023 |
Agents induction anaesthesia | ||||
-Propofol -Other | 181 (94.3) 11 (5.7) | 19 (90.5) 2 (9.5) | 162 (94.7) 9 (5.3) | 0.344 |
Agents induction analgesia | ||||
-Sufentanil -Remifentanil -other | 166 (86.5) 21 (10.9) 5 (2.6) | 20 (95.2) 1 (4.8) 0 (0) | 146 (85.4) 20 (11.7) 5 (2.9) | 0.439 |
Agents maintenance anaesthesia | ||||
-Propofol -Isoflurane -Sevoflurane -Other | 130 (68.4) 13 (6.8) 35 (18.4) 12 (6.3) | 17 (77.3) 2 (9.1) 3 (13.6) 0 (0) | 113 (67.3) 11 (6.5) 32 (19.0) 12 (7.1) | 0.503 |
Agents maintenance analgesia | ||||
-Sufentanil -Remifentanil -Other | 144 (75.0) 27 (14.1) 21 (10.9) | 17 (77.3) 4 (18.2) 1 (4.5) | 127 (74.7) 23 (13.5) 20 (11.8) | 0.537 |
Additional vasoactive medication received | ||||
-No -Yes | 11(5.6) 184 (94.4) | 1 (4.3) 22 (95.7) | 10 (5.8) 162 (94.2) | 1.000 |
Mean BIS | 43土11 | 42土11 | 43土12 | 0.786 |
Mean BIS | ||||
-<45 ->=45 | 53 (60.2) 35 (39.8) | 10 (66.7) 5 (33.3) | 43 (58.9) 30 (41.2) | 0.549 |
BIS < 45 time | 119土141 | 127土179 | 115土145 | 0.504 |
BIS < 45% | 63土55 | 62土63 | 62土53 | 1.000 |
BIS > 60 time | 7土14 | 6土14 | 8土14 | 1.000 |
BIS > 60% | 4土8 | 3土12 | 4土8 | 0.584 |
MAP < 70 time | 47土68 | 68土73 | 45土65 | 0.386 |
MAP 70 AUC | 433土644 | 606土655 | 419土640 | 0.773 |