Fig. 1
From: Blood-nerve barrier enhances chronic postsurgical pain via the HIF-1α/ aquaporin-1 signaling axis
PWMT was significantly reduced by SMIR. (A) The SMIR model was established. (B) The PWMT of the SMIR model was determined using Von Frey filaments. The PWMT in the SMIR group was significantly decreased at the first, 3rd, 7th, 14th, 21st day post-surgery (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. naive group. ##P < 0.01, ###P < 0.001 vs. sham group; n = 6), reaching the lowest value on the 7th day post-surgery