Index of consciousness monitoring during general anesthesia may effectively enhance rehabilitation in elderly patients undergoing laparoscopic urological surgery: a randomized controlled clinical trial

Table 3 Neuropsychological assessment and incidence of POCD

variable	Group control (n = 60)	Group IoC (n = 60)	t-value	P-value	SE difference (95%Cl)
MMSE score(T₀)	27.53 ± 0.75	27.57 ± 0.91	0.186	0.872^a	0.15(-0.33, 0.27)
MMSE score (T₄)	27.75 ± 1.20	27.83 ± 1.25	0.370	0.711^a	0.23(-0.53, 0.36)
MoCA score(T₀)	23.62 ± 2.78	23.73 ± 3.30	0.209	0.834^a	0.56(-1.22, 0.99)
MoCA score(T₄)	24.37 ± 1.93	25.43 ± 2.65	2.523	0.013^a	0.42(-1.90, -0.23)
POCD[n (%)]	19(31.7)	6(10.0)	8.539	0.003^b	——

Data are shown as mean ± SD or number (%).MMSE: Mini-Mental State Examination; MoCA: Montreal Cognitive Assessment; POCD: postoperative cognitive dysfunction;T₀ : 1 day before surgery; T₄ : 7 days after surgery
^a The P-value was obtained by two-sample t-test
^b The P-value was obtained by Pearson’s chi-square test
P < 0.05 was considered as statistically significant

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