Patient Characteristics | Always Room Air (n = 74) | Intermittent SO (n = 88) | Always SO (n = 40) | p-value |
---|---|---|---|---|
Age (yrs) (Mean ± SD) | 49.4 ± 15.5 | 52.6 ± 12.9 | 56.0 ± 13.9 | 0.053 |
Body Mass Index (kg/m2) (Mean ± SD) | 36.6 ± 12.3 | 36.2 ± 11.1 | 34.5 ± 12.6 | 0.440 |
Current Smoker | 8.1% (6/74) | 8.0% (7/88) | 5.0% (2/40) | 0.807 |
Oxygen Use at Home | 0.0% (0/74) | 1.1% (1/88) | 2.5% (1/40) | 1.0 |
ASA Physical Status | ||||
ASA I | 0.0% (0/74) | 0.0% (0/88) | 0.0% (0/40) | 0.603 |
ASA II | 28.4% (21/74) | 22.7% (20/88) | 30.0% (12/40) | |
ASA III | 71.6% (53/74) | 76.1% (67/88) | 67.5% (27/40) | |
ASA IV | 0.0% (0/74) | 1.1% (1/88) | 2.5% (1/40) | |
PRODIGY Score | ||||
Low (< 8) | 53.4% (39/73) | 43.2% (38/88) | 27.5% (11/40) | 0.123 |
Intermediate (8–14) | 27.4% (20/73) | 30.7% (27/88) | 40.0% (16/40) | |
High (≥ 15) | 19.2% (14/73) | 26.1% (23/88) | 32.5% (13/40) | |
SO Flow Rate (L/min) (Mean ± SD) | NA | 2.1 ± 0.7 | 1.9 ± 0.7 | 0.538 |
Surgical Demographics | ||||
High-Risk Surgerya | 6.8% (5/74) | 11.4% (10/88) | 17.5% (7/40) | 0.210 |
Open Surgery | 12.2% (9/74) | 17.0% (15/88) | 10.0% (4/40) | 0.490 |
Opioid Demographics | ||||
Opioid Naive | 81.1% (60/74) | 84.1% (74/88) | 85.0% (34/40) | 0.827 |
Multiple Opioids or concurrent CNS/Sedating Medication | 100.0% (74/74) | 97.7% (86/88) | 100.0% (40/40) | 0.270 |
Opioid Morphine Milligram Equivalents (post-surgery) (Median, IQR) | 26.9 (7.6- 90.0) | 27.1 (15.3- 60.2) | 21.5 (12.4- 76.6) | 0.798 |
Medical History | ||||
Cardiac Disorders | ||||
Aortic Aneurysm | 0.0% (0/74) | 2.3% (2/88) | 0.0% (0/40) | 0.679 |
Aortic Valve Disease | 0.0% (0/74) | 3.4% (3/88) | 0.0% (0/40) | 0.309 |
Chronic Heart Failure | 1.4% (1/73) | 2.3% (2/88) | 0.0% (0/40) | 1.000 |
Coronary Artery Disease | 4.1% (3/73) | 1.1% (1/88) | 5.0% (2/40) | 0.353 |
Hypertension | 43.2% (32/74) | 56.8% (50/88) | 47.5% (19/40) | 0.214 |
Mitral Valve Disease | 1.4% (1/74) | 1.1% (1/88) | 0.0% (0/40) | 1.000 |
Myocardial Infarction | 0.0% (0/73) | 2.3% (2/88) | 0.0% (0/40) | 0.680 |
Sepsis | 1.4% (1/74) | 1.1% (1/88) | 0.0% (0/40) | 1.000 |
Metabolism and Nutrition Disorders | ||||
Diabetes—Type I | 1.4% (1/74) | 3.4% (3/88) | 0.0% (0/40) | 0.537 |
Diabetes—Type II | 21.6% (16/74) | 14.8% (13/88) | 15.0% (6/40) | 0.471 |
Kidney Failure | 1.4% (1/74) | 2.3% (2/88) | 2.5% (1/40) | 1.000 |
Respiratory Disorders | ||||
Acute Bronchitis | 0.0% (0/74) | 1.1% (1/88) | 5.0% (2/40) | 0.149 |
Asthma | 23.0% (17/74) | 21.6% (19/88) | 7.5% (3/40) | 0.105 |
Chronic Bronchitis | 0.0% (0/74) | 1.1% (1/88) | 0.0% (0/40) | 1.000 |
Chronic Obstructive Pulmonary | 5.4% (4/74) | 4.5% (4/88) | 5.0% (2/40) | 1.000 |
Pneumonia | 0.0% (0/74) | 2.3% (2/88) | 5.0% (2/40) | 0.191 |
Sleep Disordered Breathingb | 14.9% (11/74) | 20.5% (18/88) | 25.0% (10/40) | 0.398 |
Vascular Disorders | ||||
Cerebral Aneurysm | 2.7% (2/74) | 4.5% (4/88) | 0.0% (0/40) | 0.427 |
Peripheral Vascular Disease | 1.4% (1/74) | 2.3% (2/88) | 2.5% (1/40) | 1.000 |
Stroke | 4.1% (3/73) | 3.4% (3/88) | 2.5% (1/40) | 1.000 |
Transient Ischemic Attack | 2.7% (2/73) | 1.1% (1/88) | 2.5% (1/40) | 0.678 |