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Table 2 Predictive parameters of receiver operating characteristic (ROC) curves of variable percent changes induced by supine transfer

From: Supine transfer test-induced changes in cardiac index predict fluid responsiveness in patients without intra-abdominal hypertension

Parameters

ΔCI

ΔPPV

ΔSBP

ΔDBP

AUC (CI95%)

0.88 (0.72–0.97)

0.61 (0.43–0.78)

0.54 (0.36–0.71)

0.66(0.48–0.82)

p-value versus AUC = 0.50

 < 0.01

0.25

0.678

0.09

Best cutoff value

5.5%

14%

1.7%

2.5%

Gray zone of optimal threshold

(-3% to 8%)

(-38% to 12%)

(-7% to 13%)

(-6% to 11%)

Patienst in gray zone, (number (%))

19(55%)

24(71%)

28(82%)

23(68%)

Sensitivity (CI95%)

76.5(50.1–93.2)

100(80.5–100.0)

70.6(44.0–89.7)

70.6 (44.0–89.7)

Specificity (CI95%)

88.2(63.6–98.5)

23.5(6.8–49.9)

52.9(27.8–77.0)

64.7 (38.3–85.8)

Positive predictive value (CI95%)

86.7(63.3–96.1)

56.7 (50.1–63.0)

60.0 (45.4–73.0)

66.7 (49.5–80.3)

Negative predictive value (CI95%)

78.9(61.0–90.0)

100. 0(-)

64.3 (43.2–81.0)

68.7 (49.3–83.3)

Positive likehood ratio (CI95%)

6.50(1.7–24.5)

1.31 (1.0–1.7)

1.50 (0.8–2.7)

2.00 (1.0–4.1)

Negative likehood ratio (CI95%)

0.27(0.1–0.6)

0.0 (-)

0.56 (0.2–1.3)

0.45 (0.2–1.0)

Youden index

0.65

0.24

0.24

0.35

  1. AUC Area under ROC curve, CI95% 95% confidence interval, ΔCI Percent changes in cardiac index, ΔPPV Percent changes in pulse pressure variation, ΔSBP Percent changes in systolic blood pressure, ΔDBP Percent changes diastolic blood pressure