Table 1 Hemodynamic variables at different study steps

HR (beats/min)

 Responders

96(88–114)

97(85–113)

96(88–116)

95(82–109)

 Non-responders

89(72–100)

90(73–97)

89(73–102)

90(73–95)

CVP (mmHg)

 Responders

7 (6–7)

9 (8–10)^b

6 (6–8)

8(7–9)^{b c}

 Non-responders

7 (6–8)

8 (7–9)^b

7 (6–8)

8 (7–9)^b

SBP (mmHg)

 Responders

111(94–121)

113(100–119)

108(94–121)

114(101–122)^{b c}

 Non-responders

110(102–115)

109(105–116)

109(102–115)

113(109–121)^{b c}

DBP (mmHg)

 Responders

52(45–61)

54(46–60)^b

52(47–63)

54(45–61)

 Non-responders

55(51–62)

56(50–60)

55(50–63)

58(52–60)

PPV (%)

 Responders

9(8–11)

8(7–12)

9(8–10)

8(7–11)

 Non-responders

9(8–12)

8(8–10)

9(8–11)

9(8–11)

CI (L/min/m²)

 Responders

3.5(3.1–4.3)

4.1(3.4–4.9)^b

3.5(3.2–4.3)

4.5(3.9–5.2)^{a b c}

 Non-responders

3.7(3.5–4.2)

3.8(3.5–4.2)

3.6(3.5–4.2)

3.9(3.8–4.4)