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Table 3 Logistic regression analyses for clinicians’ adherence to ACCP guidelines

From: Clinicians’ adherence to guidelines for the preoperative management of direct oral anticoagulants in a tertiary hospital: a retrospective study

Variable

Adherent group

Non-adherent group

OR (Univariate)

OR (multivariate)

Age (mean;SD)

73.84 (1.04)

73.89 (0.82)

1.0 (95%CI 0.98–1.0; p = 0.97)

-

Sex (%)

Female 35.75

Female 37.93

0.91 (95%CI 0.57–1.45; p = 0.69)

-

Male 64.25

Male 62.07

CHA2DS2VASc (mean;SD)

3.80 (0.13)

3.90 (0.14)

0.97 (95%CI 0.86–1.10; p = 0.62)

-

Antiplatelet agent (%)

Yes (89.66), No (10.34)

Yes (86.88), No (13.12)

0.76 (95%CI 0.37–1.56; p = 0.46)

-

DOAC indication (AF vs VTE) (%)

AF (71.55)

AF (71.95)

1.02 (95%CI 0.62–1.56; p = 0.94)

-

VTE (28.45)

VTE (30.22)

BMI (mean;SD)

27.09 (0.46)

26.09 (0.32)

1.04 (95%CI 1.0–1.1; p = 0.07)

1.05 (95%CI 0.99–1.1; p = 0.09)

DOAC type (%)

Rivaroxaban (37.07)

Rivaroxaban (28.05)

-

-

Edoxaban (8.62)

Edoxaban (9.50)

0.69 (95%CI 0.29–1.60; p = 0.39)

0.76 (95%CI 0.31–1.87; p = 0.55)

Apixaban (50.86)

Apixaban (58.37)

0.65 (95%CI 0.40–1.08; p = 0.10)

0.57 (95%CI 0.33–0.97; p = 0.04)

Dabigatran (3.45)

Dabigatran (4.07)

0.64 (95%CI 0.19–2.22; p = 0.48)

0.52 (95%CI 0.14–1.93; p = 0.33)

Bleeding risk (%)

High bleeding risk (59.48)

High bleeding risk (38.46)

-

-

Low/moderate bleeding risk (26.72)

Low/moderate bleeding risk (29.41)

0.59 (95%CI 0.34–1.00; p = 0.05)

0.54 (95%CI 0.46–1.50; p = 0.67)

Minimal bleeding risk (13.79)

Minimal bleeding risk (3.21)

0.27 (95%CI 0.15–0.52; p < 0.001)

0.53 (95%CI 0.24–1.13; p = 0.1)

Type of anaesthesia (%)

General (83.62)

General (58.82)

-

-

Neuraxial (4.31)

Neuraxial (4.52)

0.67 (95%CI 0.22–2.02; p = 0.48)

0.56 (95%CI 0.18–1.76; p = 0.32)

Local (11.21)

Local (35.29)

0.22 (95%CI 0.12–0.43; p < 0.001)

0.30 (95%CI 0.14–0.66; p < 0.01)

Other (0.86)

Other (1.36)

0.45 (95%CI 0.05–4.36; p = 0.49)

0.59 (95%CI 0.05–6.75; p = 0.67)

  1. DOAC direct oral anticoagulant, BMI body mass index, AF atrial fibrillation, VTE venous thromboembolism