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Table 2 Characteristics of Sensory Block and Motor Block

From: Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for ED50 determination using an up-down sequential allocation method

Parameters

Group Rop8 (n = 30)

Group Rop10 (n = 30)

P-value

Dexmedetomidine dosage

Dexmedetomidine dosage

4 µg

(n = 3)

5 µg

(n = 10)

6 µg

(n = 10)

7 µg

(n = 5)

8 µg

(n = 2)

1 µg

(n = 3)

2 µg

(n = 6)

3 µg

(n = 7)

4 µg

(n = 8)

5 µg

(n = 5)

6 µg

(n = 1)

Sensory block (to pinprick)

Highest sensory block (n, %)

T2

0

0

0

0

0

0

1 (16.7)

0

1 (12.5)

0

0

-

T3

0

0

1 (10.0)

0

0

0

0

0

1 (12.5)

0

1 (100.0)

-

T4

0

2 (20.0)

3 (30.0)

0

0

0

0

1 (14.3)

2 (25.0)

2 (40.0)

0

-

T5

0

1 (10.0)

2 (20.0)

2 (40.0)

1 (50.0)

0

1 (16.7)

1 (14.3)

0

0

0

-

T6

0

1 (10.0)

0

2 (40.0)

1 (50.0)

0

1 (16.7)

1 (14.3)

2 (25.0)

2 (40.0)

0

-

T7

0

0

0

1 (20.0)

0

0

0

0

0

0

0

-

T8

1 (33.3)

3 (30.0)

0

0

0

2 (66.7)

1 (16.7)

1 (14.3)

0

0

0

-

T9

0

1 (10.0)

0

0

0

0

2 (33.3)

1 (14.3)

1 (12.5)

0

0

-

T10

2 (66.7)

2 (20.0)

4 (40.0)

0

0

1 (33.3)

0

2 (28.6)

1 (12.5)

1 (20.0)

0

-

Onset time to T10 (min)

4.3 ± 2.8

4.3 ± 2.8

1

Time to highest level (min)

9.0 ± 2.1

8.6 ± 2.9

0.543

Duration of sensory block (min)

169.7 + 62.0

192.4 + 72.4

0.197

Motor block

Bromage Score (n, %)

0

0

0

0

0

0

0

0

0

0

0

0

-

1

0

0

0

0

0

0

0

0

0

0

0

-

2

1 (33.3)

1 (11.1)

1 (11.1)

0

0

0

0

0

1 (12.5)

0

0

-

3

2 (66.7)

9 (88.9)

9 (88.9)

5 (100.0)

2 (100.0)

3 (100.0)

6 (100.0)

7 (100.0)

7 (87.5)

5 (100.0)

1 (100.0)

-

No. of patients with incomplete

motor block (n, %)

3 (10.0)

1 (3.3)

0.612

Onset time to Bromage score = 1 (min)

7.37 ± 6.27

3.93 ± 2.12

0.006*

Onset time to Bromage score = 2 (min)

11.03 ± 8.16

7.10 ± 2.99

0.016*

Onset time to Bromage score = 3 (min)

15.78 ± 8.34

14.24 ± 8.13

0.472

Duration of motor block (min)

343.6 ± 73.1

372.5 ± 78.4

0.145

  1. Notes: Sensory block refer to the highest level of block within 10 min after intrathecal injection. Motor block refer to the greatest degree of block during the surgery. Data are presented as number (percentage) or mean ± SD. *P < 0.05 versus Group Rop8