Fig. 2From: Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for ED50 determination using an up-down sequential allocation methodIndividual response to intrathecal dexmedetomidine coadministered with ropivacaine at the corresponding dose (µg). The ED50 of intrathecal dexmedetomidine coadministered with ropivacaine for cesarean section was 5.9 µg (95% CI, 4.9 to 7.4 µg) in Group Rop8 and 3.1 µg (95% CI, 0.1 to 4.8 µg) in Group Rop10 using probit regression. An effective intrathecal block is denoted by a filled circle, while an ineffective block is denoted by an open circle. Dashed lines indicate the position of the estimates of ED50Back to article page