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Table 1 Airway and transpulmonary pressures at 8 ml kg-1 between the two ventilation regimes

From: Pressure- vs. volume-controlled ventilation and their respective impact on dynamic parameters of fluid responsiveness: a cross-over animal study

Ventilation parameter

Fluid state

VCV

PCV

P

Peak Inspiratory Pressure [cmH2O]

Baseline

22.3 [20.6–25.1]

18.5 [17.5–19.2]

0.005

Hypovolaemia

23.4 [20.7–25.3]

18.7 [17.1–19.3]

0.005

Resuscitation I

23.1 [20.4–25.0]

18.9 [16.9–19.5]

0.010

Resuscitation II

23.6 [21.2–25.4]

18.0 [16.8–19.0]

< 0.001

Plateau Pressure [cmH2O]

Baseline

16.7 [15.7–19.5]

18.5 [17.5–19.2]

0.195

Hypovolaemia

16.3 [15.4–16.6]

18.7 [17.1–19.3]

0.005

Resuscitation I

15.6 [14.8–16.4]

18.9 [16.9–19.5]

0.010

Resuscitation II

16.1 [15.4–16.5]

18.0 [16.8–19.0]

0.003

Driving Pressure [cmH2O]

Baseline

7.2 [5.9–7.5]

9.0 [8.2–10.8]

0.050

Hypovolaemia

6.9 [6.4–7.9]

8.7 [7.8–11.2]

0.015

Resuscitation I

6.5 [6.1–7.1]

9.4 [7.6–10.9]

0.002

Resuscitation II

7.2 [6.2–7.5]

8.8 [7.6–10.4]

0.005

Transpulmonary Inspiratory Pressure [cmH2O]

Baseline

4.8 [1.3–9.2]

7.1 [2.7–9.3]

0.383

Hypovolaemia

7.0 [2.7–7.5]

7.3 [6.2–9.7]

0.383

Resuscitation I

3.6 [2.4–5.4]

6.8 [4.2–9.3]

0.053

Resuscitation II

3.3 [2.6–4.5]

6.8 [4.7–7.5]

0.026

Transpulmonary Expiratory Pressure [cmH2O]

Baseline

1.4 [-2.0–2.5]

2.3 [-1.6–2.8]

0.456

Hypovolaemia

3.6 [-0.9–4.5]

3.2 [-0.6–5.5]

0.902

Resuscitation I

0.3 [-1.8–3.2]

0.8 [-1.1–3.6]

0.589

Resuscitation II

-1.4 [-3.0–1.2]

0.6 [-1.4–1.3]

0.318

Transpulmonary Driving Pressure [cmH2O]

Baseline

3.3 [2.9–5.1]

6.1 [4.3–7.4]

0.038

Hypovolaemia

4.2 [2.9–5.9]

6.9 [3.5–8.5]

0.065

Resuscitation I

3.8 [2.9–4.8]

6.4 [4.7–8.3]

0.021

Resuscitation II

4.5 [3.5–5.5]

6.2 [4.5–6.9]

0.050

  1. Data are presented as median [IQR]. VCV, volume-controlled ventilation; PCV, pressure-controlled ventilation. P < 0.05 is considered statistically significant and respective values are printed in bold.