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Table 1 Clinical variables between no anemia group and anemia group, before and after propensity score matching

From: Association between preoperative anemia and postoperative short-term outcomes in patients undergoing colorectal cancer surgery - a propensity score matched retrospective cohort study

Variables

 

Cohort before propensity matching

Cohort after propensity matching

No anemia

n = 1140

Anemia

n = 754

SMD a

No anemia

n = 609

Anemia

n = 609

SMD a

ASA Status

I–II

981 (86.1)

601 (79.7)

0.158

512 (84.1)

496 (81.4)

0.065

 

III–IV

159 (13.9)

153 (20.3)

 

97 (15.9)

113 (18.6)

 

Gender

Female

439 (38.5)

311 (41.2)

0.056

257 (42.2)

241 (39.6)

0.053

Current Smoking Status

(within 12 months)

Yes

266 (23.3)

142 (18.8)

0.115

142 (23.3)

123 (20.2)

0.080

Cardiovascular Comorbiditiesb

Yes

60 (5.3)

67 (8.9)

0.127

35 (5.7)

50 (8.2)

0.087

Pulmonary Comorbiditiesc

Yes

140 (12.3)

118 (15.6)

0.093

95 (15.6)

89 (14.6)

0.027

History of Laparotomy

Yes

178 (15.6)

130 (17.2)

0.043

109 (17.9)

109 (17.9)

< 0.001

Hypoalbuminemia

< 3.5 g L− 1

12 (1.1)

94 (12.5)

0.345

12 (2.0)

24 (3.9)

0.060

Hypertension

Yes

329 (28.9)

263 (34.9)

0.126

194 (31.9)

207 (34.0)

0.045

Diabetes

Yes

157 (13.8)

119 (15.8)

0.055

77 (12.6)

94 (15.4)

0.077

TNM staged

0–II

664 (58.2)

404 (53.6)

0.093

347 (57.0)

326 (53.5)

0.069

 

III–IV

476 (41.8)

350 (46.2)

 

262 (43.0)

283 (46.5)

 

Preoperative Chemoradiotherapy

Yes

276 (24.3)

250 (33.2)

0.190

212 (34.8)

211 (34.6)

0.003

Tumor Location

Rectum

682 (59.8)

317 (42.0)

0.360

293 (48.1)

293 (48.1)

< 0.001

 

Colon

458 (40.2)

437 (58.0)

 

316 (51.9)

316 (51.9)

 

Age

Years

60.0

[52.0, 68.0]

64.0

[55.0, 72.0]

0.240

62.0

[54.0, 69.0]

63.0

[54.0, 71.0]

0.055

BMI

Kg m-2

23.4

[21.5, 25.7]

22.3

[20.4, 24.6]

0.311

22.8

[20.8, 24.8]

22.5

[20.7, 24.8]

0.052

LMR

 

4.7 [3.3, 6.1]

3.6 [2.4, 4.9]

0.420

4.1 [2.8, 5.4]

3.8 [2.6, 5.2]

0.061

Duration of surgery

Min

210.0

[175.0, 254.0]

220.0

[184.0, 269.0]

0.124

215.0

[175.0, 260.0]

220.0

[182.0, 268.0]

0.064

Surgical Approach

Laparoscopic

1096 (96.1)

717 (95.1)

0.048

578 (94.9)

582 (95.6)

0.030

 

Open

44 (3.9)

37 (4.9)

 

31 (5.1)

27 (4.4)

 

Robot-assisted Surgery

Yes

129 (11.3)

67 (8.9)

0.085

67 (11.0)

62 (10.2)

0.029

Preventive Stoma

Yes

320 (28.1)

167 (22.1)

0.143

170 (27.9)

153 (25.1)

0.067

Resection of Adjacent Organs

Yes

71 (6.2)

79 (10.5)

0.139

44 (7.2)

57 (9.4)

0.070

Intraperitoneal Chemotherapy

Yes

25 (2.2)

13 (1.7)

0.036

14 (2.3)

10 (1.6)

0.050

Perioperative Blood Transfusions

Yes

26 (2.3)

95 (12.6)

0.311

24 (3.9)

24 (3.9)

< 0.001

  1. Data are presented as n (%) or median [IQR]
  2. SMD standardized mean difference, ASA American society of anesthesiologists, BMI body mass index, LMR lymphocyte-to-monocyte ratio, TNM tumor node metastasis
  3. a SMD ≤ 0.092 and 0.112were considered to be balanced between the two groups before and after matching, respectively21
  4. b Cardiovascular Comorbidity includes ischemic heart disease, automated implantable cardioverter defibrillators insertion, cardiac valve replacement, pacemaker insertion, cardiomyopathy, percutaneous coronary intervention, coronary artery bypass graft, atrial fibrillation
  5. c Pulmonary Comorbidity includes asthma, chronic obstructive pulmonary disease, bronchiectasis, emphysema
  6. d TNF 0 stage that pathologic complete response (ypCR)
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BMC Anesthesiology

ISSN: 1471-2253

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