Table 1 Baseline characteristics of septic patients

Age (years)

66 (56–78)

60 (50–76)

Weight (kg)

84 (68–90)

76 (70–95)

Time to first dose (h)

15 (3–24)

10 (5–15)

MAP (mmHg)

80 (71–94)

80 (75–85)

HR (bpm)

125 (95–135)

108 (91–112)

Lactate level (mmol/L)

2.4 (1.3–4.7)

1.6 (1.4-3.0)

PBR_5 − 25 (μm)

2.00 (1.76–2.44)

2.17 (1.97–2.33)

PBR_5 − 9 (μm)

1.13 (1.01–1.25)

1.16 (1.09–1.29)

PBR_{10 − 19} (μm)

2.09 (1.81–2.55)

2.15 (1.98–2.42)

PBR_{20 − 25} (μm)

2.61 (2.45–3.21)

2.77 (2.48–2.99)

TVD (mm/mm²)

21.5 (19.6–24.3)

21.8 (18.8–23.1)

PVD (mm/mm²)

16.8 (15.3–20.8)

18.1 (14.4–21.5)

PPV (%)

81.8 (69.5–89.6)

83.4 (78.4–90.9)

MFI

1.54 (1.31–1.85)

1.83 (1.5–1.92)

FHI (AU)

0.25 (0.15–0.36)

0.28 (0.22–0.44)

Source of infection:

Pneumonia n (%)

4 (33.3)

5 (45.5)

Abdomen n (%)

7 (58.4)

1 (9.1)

Urinary tract n (%)

1 (8.3)

3 (27.3)

Other n (%)

2 (18.1)

PEEP (cmH₂O)

FiO₂ (%)

5 (5–8)

60 (40–70)

6 (5–8)

60 (50–65)

pH

7.33 (7.22–7.38)

7.24 (7.19–7.38)

pO₂ (mmHg)

111 (80–138)

71 (58–121)

pCO₂ (mmHg)

39 (34–59)

35 (31–42)

HCO₃⁻ (mmol/L)

21 (17–25)

16 (14–21)

Hb (g/L)

117 (95–139)

106 (83–115)

CRP (mg/L)

214 (129–395)

277 (218–431)

Glucose level (mmol/L)

6.8 (5.5–9.8)

8.6 (6.9–12.8)