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Table 5 Summary of Findings. This table presents a summary of the findings of this overview of SRs. It summarises the 20 recommendations of the Levy et al. (2020) [8] and the Forget et al. (2022) [2] consensus statements, states the presence or not of relevant SRs and/or meta-analyses, and the respective degree of certainty (“Uncertain” in the absence of SR)

From: Opioid prescribing for acute postoperative pain: an overview of systematic reviews related to two consensus statements relevant at patient, prescriber, system and public health levels

Recommendation domain

SRs/meta-analysis quality

Degree of certainty

Levy et al.’s (2020) [8] priorities

Risks with opioids

1 SR with MA (critically low quality)

Low

Preoperative optimisation

2 SRs with MA + 1 SR without MA (high – critically low quality)

High – low

Functional outcomes-based analgesia

1 SR without MA (low quality)

Low

Multimodal analgesia

1 SR without MA (quality could not be assessed)

Uncertain

Long-acting opioids

No SRs

Uncertain

Patient-centred treatment duration

2 SRs without MA (critically low quality)

Low

Post-discharge repeat prescriptions

No SRs

Uncertain

Opioid-induced ventilatory impairment

No SRs

Uncertain

Modifiable factors

No SRs

Uncertain

Safe opioid storage and disposal

3 SRs without MA (critically low quality

Low

Forget et al.’s (2022) [2] priorities

Opioid Stewardship Steering Committee

1 SR without MA (critically low quality)

Low

Safe and accountable opioid use policies

No SRs

Uncertain

Policies on opioid prescriptions determinants

No SRs

Uncertain

Opioid treatment (dose and duration) policies

1 SR with MA (low quality)

Low

Follow-up and referral guidelines

No SRs

Uncertain

Monitoring of opioid prescriptions

No SRs

Uncertain

Preventing obstacles to access appropriate opioid prescription

No SRs

Uncertain

Opioid disposal

No SRs

Uncertain

Benchmarking

No SRs

Uncertain

Improved interaction primary/secondary care

No SRs

Uncertain

  1. SR Systematic review