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Table 2 The characteristics of included systematic reviews. This table describes the characteristics of each study that is included in this overview. The author, year of publication, country, number of primary studies, number of participants, search period, intervention, primary outcome measures and quality evaluation method of each review are all stated

From: Opioid prescribing for acute postoperative pain: an overview of systematic reviews related to two consensus statements relevant at patient, prescriber, system and public health levels

Authors

Year

Country

Included study design

No. of studies

(total no. of participants)

Search period

Intervention

Primary outcome measures

Quality evaluation method

Albrecht et al. [27]

2019

Switzerland

RCTs

27 (1,630)

Up to 30 June 2019

High-dose vs low-dose intraoperative opioids

Pain score at rest at 24 postoperative hours

GRADE

Arwi & Schug [23]

2020

Australia

NRSIs

28 (661,441)

Up to 1 December 2018

Opioids prescribed at discharge after inpatient care

The potential for harm of discharge opioids including excessive prescribing of discharge opioids, improper storage and disposal of opioids

Newcastle–Ottawa Quality Assessment Scale

Baamer et al. [21]

2022

UK

RCTs and NRSIs

31 (12,498)

Up to August 2020

Unidimensional and functional assessment tools used for postoperative patients

Measurement error, cross-cultural validity, reliability, responsiveness, and hypothesis testing for construct validity

Modified version of the Newcastle–Ottawa Quality Assessment Scale; and COSMIN criteria for methodological quality

Bicket et al. [16]

2017

USA

RCTs and NRSIs

6 (810)

Up to 20 July 2016

Opioids prescribed for acute postoperative pain

The number of patients reporting any unused opioids

Newcastle–Ottawa Quality Assessment Scale

Feinberg et al. [24]

2018

Canada

NRSIs

11 (3,562)

Up to 17 December 2016

Opioids prescribed for acute postoperative pain

The quantity of opioid medication used post-discharge

None

Horn et al. [17]

2020

USA

RCTs and NRSIs

43 (Not reported)

Not reported

Preoperative psychoeducational methods

The quality of preoperative psychoeducation and its effects on the outcome of surgery

Oxford levels of evidence

Lamplot et al. [18]

2021

USA

RCTs and NRSIs

16 (3,077)

Up to 2 October 2019

Opioids prescribed for acute postoperative pain

Rates of disposal of unused opioids and the reported disposal mechanisms for unused opioids

SIGN checklists for cohort studies and RCTs

Lawal et al. [19]

2020

USA

NRSIs

33 (1,922,743)

Up to 30 June 2019

Postoperative opioid use

Risk factors associated with prolonged opioid use after surgery

Newcastle–Ottawa Quality Assessment Scale

Martinez et al. [25]

2017

France

RCTs

135 (13,287)

Up to August 2015

Non-opioid analgesics and tramadol prescribed for acute postoperative pain

Morphine consumption, pain, incidence of nausea, vomiting at 24 h and severe adverse effects

Cochrane Risk of Bias tool

Powell et al. [22]

2016

UK

RCTs

105 (10,302)

Up to May 2014

Psychological preparation in adults undergoing elective surgery under general anaesthetic

Postoperative outcomes including pain, behavioural recovery, length of stay and negative affect

Cochrane Risk of Bias tool

Sobol-Kwapinska et al. [26]

2016

Poland

Not reported

53 (10,749)

January 1960 – 30 November 2015

Preoperative psychological factors

Acute postoperative pain and analgesic consumption

Quality in Prognostic Studies tool

Wetzel et al. [20]

2018

USA

RCTs and NRIs

8 (2,272)

January 2000 – March 2018

Behavioural intervention associated with postoperative prescribing

Postoperative opioid prescribing

Quality Assessment Tool for Quantitative Studies

  1. USA United States of America, UK United Kingdom, RCTs Randomised controlled trials, NRSIs Non-randomised studies of intervention, GRADE Grading of Recommendations, Assessment, Development and Evaluations, SIGN Scottish Intercollegiate Guidelines Network