Table 2 Cox proportional hazard regression analysis for post-hospital mortality in critically ill surgical patients
Univariable analysis | Multivariable analysis | |||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | P value | |
Basic characteristics | ||||
Age ≥ 65 years | 1.880 (1.668–2.118) | < 0.001 | 1.253 (1.104–1.422) | < 0.001 |
Sex (Female) | 1.367 (1.202–1.555) | < 0.001 | 1.379 (1.210–1.572) | < 0.001 |
Body mass index | 0.903 (0.890–0.917) | < 0.001 | 0.919 (0.905–0.933) | < 0.001 |
Charlson comorbidity index ≥ 2 | 2.787 (2.460–3.156) | < 0.001 | 2.200 (1.929–2.508) | < 0.001 |
Severity and managements | ||||
APACHE II score | 1.069 (1.057–1.082) | < 0.001 | 1.016 (1.004–1.029) | 0.008 |
Presence of shock | 1.441 (1.273–1.631) | < 0.001 | 0.936 (0.819–1.070) | 0.330 |
Scheduled surgery | 0.736 (0.653–0.828) | < 0.001 | 0.858 (0.757–0.973) | 0.017 |
Mechanical ventilation (≥ 3 days) | 2.116 (1.879–2.383) | < 0.001 | 1.061 (0.911–1.235) | 0.446 |
Fluid balance day 1–3, per liter increment | 1.081 (1.054–1.108) | < 0.001 | 0.992 (0.966–1.018) | 0.523 |
Positive microbiological culture | 2.610 (2.318–2.938) | < 0.001 | 1.577 (1.359–1.829) | < 0.001 |
Laboratory data | ||||
WBC counts, per 103/µL increment | 1.025 (1.011–1.038) | < 0.001 | 1.024 (1.010–1.037) | < 0.001 |
Haemoglobin, per 1 g/dL increment | 0.998 (0.998–0.999) | < 0.001 | 1.000 (0.999-1.000) | 0.533 |
Platelet, per 103/µL increment | 0.728 (0.702–0.755) | < 0.001 | 0.831 (0.798–0.867) | < 0.001 |
Creatinine, higher than 1.5 mg/dL | 2.133 (1.856–2.452) | < 0.001 | 0.831 (0.682–1.013) | 0.066 |
BUN/Albumin ratio, per 10 increment | 1.803 (1.695–1.918) | < 0.001 | 1.258 (1.127–1.405) | < 0.001 |