All n = 8,073 | Survivor n = 6,981 | Non-survivor n = 1,092 | p value | |
---|---|---|---|---|
Basic characteristics | ||||
Age, years | 60.4 ± 15.8 | 59.4 ± 15.7 | 67.2 ± 14.7 | < 0.001 |
Male | 5073 (62.8%) | 4314 (61.8%) | 759 (69.5%) | < 0.001 |
Body mass index | 24.3 ± 4.4 | 24.5 ± 4.4 | 22.7 ± 4.2 | < 0.001 |
Charlson Comorbidity Index | 1.6 ± 1.4 | 1.5 ± 1.4 | 2.2 ± 1.5 | < 0.001 |
Severity of critical illness | ||||
APACHE II score | 20 ± 5.5 | 19.8 ± 5.5 | 21.7 ± 5.3 | < 0.001 |
Presence of shock | 2288 (28.3%) | 1902 (27.2%) | 386 (35.3%) | < 0.001 |
Surgical divisions | < 0.001 | |||
Cardiovascular surgery | 1794 (22.2%) | 1673 (24.0%) | 121 (11.1%) | < 0.001 |
Neurosurgery | 4169 (51.6%) | 3778 (54.1%) | 391 (35.8%) | |
Major abdomen surgery | 854 (10.6%) | 616 (8.8%) | 238 (21.8%) | |
Others | 1256 (15.6%) | 914 (13.1%) | 342 (31.3%) | |
Managements in ICU | ||||
Emergent surgery | 1297 (16.1%) | 1144 (16.4%) | 153 (14%) | 0.052 |
Scheduled surgery | 4814 (59.6%) | 4233 (60.6%) | 581 (53.2%) | < 0.001 |
Mechanical ventilation (> 3 days) | 2454 (30.4%) | 1945 (27.9%) | 509 (46.6%) | < 0.001 |
Receiving RRT | 290 (3.6%) | 216 (3.1%) | 74 (6.8%) | < 0.001 |
Fluid balance day 1–3, positive | 5987 (65.5%) | 4354 (62.4%) | 1633 (75.4%) | < 0.001 |
Positive microbiological culture | 2379 (29.5%) | 1834 (26.3%) | 545 (49.9%) | < 0.001 |
Laboratory data | ||||
White blood cell count (/µl) | 10,697 ± 4022 | 10643.1 ± 3685.5 | 11041.9 ± 5713.5 | 0.026 |
Haemoglobin (g/dL) | 11.4 ± 1.9 | 11.5 ± 1.9 | 10.5 ± 1.7 | < 0.001 |
Platelet (103/µL) | 201.3 ± 84.8 | 203.0 ± 83.1 | 190.4 ± 94.1 | < 0.001 |
Creatinine (mg/dL) | 1.2 ± 1.3 | 1.1 ± 1.3 | 1.4 ± 1.5 | < 0.001 |
BUN (mg/dL) | 20.3 ± 14.3 | 19.4 ± 13.2 | 26.2 ± 19.0 | < 0.001 |
Albumin (mg/dL) | 3.6 ± 0.7 | 3.6 ± 0.7 | 3.2 ± 0.7 | < 0.001 |
Ratio of BUN/Albumin | 6.2 ± 5.3 | 5.8 ± 4.8 | 8.9 ± 7.4 | < 0.001 |
Outcomes | ||||
ICU length of stay, days | 6.4 ± 4.8 | 5.8 ± 4.5 | 8.1 ± 5.0 | < 0.001 |
Hospital length of stay, days | 17.0 ± 9.7 | 16.3 ± 9.3 | 19.1 ± 10.7 | < 0.001 |
Mortality at distinct time points | ||||
30-day mortality | 63 (0.78%) | NA | 63 (5.8%) | NA |
90-day mortality | 329 (4.1%) | NA | 329 (30.1%) | NA |