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Table 1 Comparison by duration of HFNC (less than 24 h versus greater than 24 h) for patients with ARF due to COVID-19 pneumonia who failed HFNC and were subsequently intubated

From: Delayed intubation associated with in-hospital mortality in patients with COVID-19 respiratory failure who fail heated and humified high flow nasal canula

 

LESS THAN 24H

OVER 24H

TOTAL

P VALUES

TOTAL PATIENT VOLUME

432

896

1328

 

AVG. AGE (STD DEV)

63 (14.9)

65 (13)

64 (13.68)

0.0002

SEX (MALE), N (%)

246 (56.9)

544 (60.7)

790 (59.5)

0.19

COPD, N (%)

131 (30.3)

301 (33.6)

432 (32.5)

0.23

HF, N (%)

113 (26.2)

170 (19)

283 (21.3)

0.003

DM, N (%)

133 (30.8)

239 (26.7)

372 (28)

0.12

CKD, N (%)

101 (23.4)

211 (23.6)

312 (23.5)

0.95

HTN, N (%)

300 (69.4)

633 (70.7)

933 (70.3)

0.65

 ≥ 1 COMORBIDITY, N (%)

372 (86.1)

752 (83.9)

1124 (84.6)

0.30

TROPONIN (> 28NG/L), N (%)

93 (21.5)

161 (18)

254 (19.1)

0.12

CREATININE (> 1.5 MG/DL), N (%)

85 (19.7)

168 (18.8)

253 (19.1)

0.69

CRP (> 100 MG/L), N (%)

132 (30.6)

275 (30.7)

407 (30.7)

0.96

LYMPHOCYTES (< = 1 ΜL), N (%)

243 (56.3)

545 (60.8)

788 (59.3)

0.32

NT-PROBNP (> 88PG/ML), N (%)

132 (30.6)

269 (30)

401 (30.2)

0.84

  1. Table 1. Comparison of covariates: age, sex, comorbidities (COPD, HF, DM, CKD, hypertension), baseline laboratory values (CRP [> 100 mg/L or <  = 100 mg/L], Troponin I [> 28 ng/L or <  = 28 ng/L], NT–proBNP [> 88 pg/mL or <  = 88 pg/mL], Lymphocyte Count [> = 1.0 µL or < 1.0 µL] and Creatinine [< = 1.5 mg/dL or > 1.5 mg/dL]), by duration of HFNC (less than 24 h vs. greater than 24 h)