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Table 1 Patient demographics across the two groups (Per-protocol)

From: The impact of semi-upright position on severity of sleep disordered breathing in patients with obstructive sleep apnea: a two-arm, prospective, randomized controlled trial

 

Control (n = 14)

Intervention (n = 21)

P value

Standardized Mean Difference

Age (years)

63 ± 10

65 ± 12

0.60

0.188

BMI (kg/m2)

32.8 ± 4

35.2 ± 7

0.26

0.420

Neck Circumference (cm)

43.3 ± 3

41.0 ± 3

0.04

0.752

Gender F/M

5/9

14/7

0.09

0.651

STOP-Bang score

4.5 ± 1

4.5 ± 1

0.95

0.020

Co-morbidity

 Hypertension

7

12

0.74

0.144

 Gastroesophageal reflux

2

7

0.26

0.459

 Diabetes Mellitus

1

6

0.20

0.583

 Smoker

2

2

1.00

0.147

 Asthma

1

3

0.64

0.232

 COPD

1

1

1.00

0.101

 CAD

3

0

0.06

0.739

Type of surgery

  

0.65

0.707

 Orthopedic

8

12

  

 General

5

6

  

 Gynecology

0

2

  

 Urology

1

0

  

Type of Anesthesia

  

1.00

0.048

 General

7

10

  

 Spinal

7

11

  

ASA Status

  

0.16

0.589

 II

8

7

  

 III

5

14

  

Total amount of opioids (in mg IV morphine equivalents)

 1st 24 h

10.3 [5.3—19.8]

11.0 [5.—20]

0.84

0.080

 1st 48 h

21.4 [13.3 – 44.4]

33.4 [15.0—55.0]

0.45

0.186

 1st 72 h

25.8 [14.2—60.50]

41.4 [25.0—81.5]

0.29

0.259

Preoperative sleep study data between the two groups

 AHI

18.1 ± 13.3

21.4 ± 13.1

0.48

0.246

 OAI

6.1 ± 3.7

11.7 ± 9.2

0.04

0.807

 OAHI

14.6 ± 7.2

20.7 ± 12.6

0.11

0.593

 CAI

3.7 ± 9.5

0.7 ± 1.4

0.16

0.444

 HI

8.6 ± 5.2

9.0 ± 7.3

0.84

0.071

 ODI

15.5 [13.5—23.7]

17.9 [12.1—39.1]

0.57

0.281

 CT90

0.7 [0.1—1.2]

3.8 [0.4 – 6.1]

0.04

0.804

 Average SaO2

93.4 ± 1.27

93.1 ± 2.4

0.71

0.137

 Lowest SaO2

83.2 ± 5.0

79.1 ± 6.1

0.04

0.748

  1. Data are expressed as mean (SD) or median (interquartile range IQR) where appropriate. Standardized Mean Difference was calculated using R package tableone
  2. BMI body mass index, COPD chronic obstructive pulmonary disease, CAD coronary artery disease, OR operating room, h hours, AHI Apnea–Hypopnea Index, Apnea index average number of apnea episodes per hour, Arousal \index number of arousals × 60 / Total sleep time, CAI Central Apnea Index: total number of central apneas per hour, CT90 cumulative percentage of Total sleep time with oxygen desaturation below 90%, HI Hypopnea index, average number of hypopnea episodes per hour, OAHI Obstructive Apnea Hypopnea Index, total number of obstructive apneas and hypopneas per hour, OAI Obstructive Apnea Index: total number of obstructive apneas divided by Total sleep time, ODI Oxygen Desaturation Index, number of events with oxygen desaturation below 4% threshold in one hour, REM% Time spent in rapid eye movement stage of sleep, SaO2 saturation of oxygen in hemoglobin