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Table 2 Risk factors for failed weaning from supplemental oxygen on univariate analysis

From: Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study

Variable

Odds ratio (95% CI)

P-value

Age > 65 years

2.20 (1.91 to 2.53)

< 0.001

Male sex

2.06 (1.79 to 2.38)

< 0.001

Body mass index ≥ 30 kg/m2

1.44 (1.12 to 1.82)

0.003

Hypertension

2.04 (1.76 to 2.35)

< 0.001

Diabetes mellitus

2.22 (1.88 to 2.61)

< 0.001

Chronic obstructive pulmonary disease

2.40 (1.70 to 3.31)

< 0.001

ASA physical status ≥ III

2.56 (2.13 to 3.05)

< 0.001

Smoking history within 6 months

1.70 (1.40 to 2.05)

< 0.001

Preoperative SpO2 < 92% in room air

3.85 (2.67 to 5.42)

< 0.001

Major abdominal surgery*

3.54 (3.02 to 4.16)

< 0.001

Duration of surgery > 2 h

2.31 (1.98 to 2.70)

< 0.001

Intraoperative fluid infusion > 1,500 mL

2.65 (2.21 to 3.16)

< 0.001

Intraoperative transfusion

2.04 (1.37 to 2.93)

< 0.001

Estimated blood loss > 400 mL

2.51 (1.94 to 3.22)

< 0.001

Inhaled anesthesia

1.68 (1.40 to 2.02)

< 0.001

Use of sugammadex during the emergence

0.94 (0.81 to 1.10)

0.455

Postoperative pain of NRS ≥ 4/10

1.98 (1.66 to 2.38)

< 0.001

Postoperative nausea and vomiting

1.02 (0.77 to 1.33)

0.893

Hypothermia during the PACU stay†

2.49 (2.14 to 2.88)

< 0.001

  1. *Major abdominal surgery included exploratory laparotomy, gastrointestinal surgery, hepato-pancreato-biliary surgery, nephrectomy, adrenalectomy, prostatectomy, hysterectomy, and gynecologic debulking surgery. Core temperature measured at the tympanic membrane below 36.0 ℃
  2. CI = confidence interval; ASA = American Society of Anesthesiologists; SpO2 = oxygen saturation measured by pulse oximetry; NRS = numeric rating scale; PACU = postanesthesia care unit