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Table 2 Blood pressure reduction from the baseline at each time point and mean differences between the groups

From: Post-induction hypotension with remimazolam versus propofol in patients routinely administered angiotensin axis blockades: a randomized control trial

  

ΔBPT1

ΔBPT2

ΔBPT3

ΔBPT4

ΔBPT5

MBP

Propofol

30.0 ± 14.5 *

10.5 ± 22.8

27.8 ± 13.3

29.8 ± 10.3

29.4 ± 11.9

Remimazolam

20.4 ± 13.9

12.0 ± 18.9

23.5 ± 13.6

26.7 ± 10.1

24.2 ± 11.9

Mean differences (95% CI)

9.6 (3.3–15.9)

-1.5 (-10.8–7.7)

4.3 (-1.7–10.2)

3.1 (-1.4–7.6)

5.2 (0.0–10.5)

SBP

Propofol

51.1 ± 25.5 *

26.6 ± 36.3

50.7 ± 23.0

54.3 ± 18.3

52.1 ± 21.2

Remimazolam

34.9 ± 22.4

25.7 ± 28.4

42.5 ± 20.6

46.1 ± 17.2

43.6 ± 20.6

Mean differences (95% CI)

16.3 (5.6–26.9)

0.9 (-13.6–15.3)

8.2 (-1.5–17.8)

8.3 (0.4–16.1)

8.5 (-0.7–17.8)

DBP

Propofol

22.5 ± 12.2 *

5.1 ± 20.0

20.3 ± 13.3

21.2 ± 10.0

21.0 ± 11.4

Remimazolam

14.5 ± 12.8

7.2 ± 17.7

16.8 ± 14.0

19.7 ± 11.4

16.8 ± 10.7

Mean differences (95% CI)

8.0 (2.5–13.6)

-2.1 (-10.4–6.3)

3.5 (-2.5–9.5)

1.5 (-3.2–6.2)

4.2 (-0.7–9.2)

  1. ΔBP, decrease in the BP at each time point; T1, T2, T3, T4 and T5, were baseline, immediately before the first attempt of intubation, a minute after intubation, 5 min after intubation, 10 min after intubation, and 15 min after intubation, respectively; CI confidence interval, MBP Mean blood pressure, SBP systolic blood pressure, DBP diastolic blood pressure
  2. *P < 0.01; Bonferroni correction was applied for each variable