The relationship between longer leukocyte telomeres and dNCR in non-cardiac surgery patients: a retrospective analysis

Table 3 Associations between LTLs and dNCR

Predictors	Univariable Analysis^a		Multivariable logistic regression analysis^b
Predictors	Odds Ratio (95% confidence interval)	P value	Odds Ratio (95% confidence interval)	P value
LTL	14.82(4.01–54.84)	< 0.001**	12.33(3.29–46.24)	< 0.001**
Age	1.07(1.01–1.13)	0.017*	1.05(0.99–1.12)	0.0696
Sex	0.93(0.45–1.93)	0.842	-	-
Education	0.96(0.88–1.05)	0.402	-	-
MMSE	0.91(0.81–1.02)	0.110	-	-

The relationship between LTL and the occurrence of dNCR was determined with multivariable logistic regression analysis. We included the LTL, significant perioperative variables (P ≤ 0.1), and the well-recognized dNCR risk factors, such as sex, age, and education levels, in existing studies in the multivariable logistic regression model. The backward logistic regression method was used
Abbreviations: dNCR delayed neurocognitive recovery, LTL leukocyte telomere length, MMSE Mini-Mental State Examination
^aOccurrence of postoperative cognitive dysfunction was modeled as a function of a single predictor
^bOccurrence of postoperative cognitive dysfunction was modeled as a function of all predictors
^*P < 0.05; **P < 0.001

ISSN: 1471-2253