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Table 1 Baseline characteristics and surgical data

From: Effects of penehyclidine hydrochloride combined with dexmedetomidine on pulmonary function in patients undergoing heart valve surgery: a double-blind, randomized trial

 

Group C (n = 43)

Group P (n = 45)

Group D (n = 43)

Group PD (n = 44)

P value

Gender (M/F), n

23/20

19/26

20/23

21/23

0.776

Age (yr)

48.4 ± 7.6

47.1 ± 9.9

50.2 ± 8.0

48.9 ± 6.6

0.350

Height (cm) (cm)

159.3 ± 6.8

158.2 ± 5.9

158.7 ± 6.5

158.1 ± 6.3

0.788

Weight (kg)

56.1 ± 8.3

56.9 ± 7.1

56.4 ± 6.2

55.4 ± 6.0

0.788

ASA

    

0.932

 II, n (%)

17 (39.5)

20 (44.4)

20 (46.5)

19 (43.2)

 

 III, n (%)

26 (60.5)

25 (55.6)

23 (53.5)

25 (56.8)

 

NYHA

    

0.973

 II, n (%)

18 (41.9)

20 (44.4)

17 (39.5)

18 (40.9)

 

 III, n (%)

25 (58.1)

25 (55.6)

26 (60.5)

26 (59.1)

 

Comorbidities n (%)

 Hypertension, n (%)

12 (36.4)

12 (26.7)

9 (20.0)

11 (25.0)

0.455

 Diabetes, n (%)

8 (18.6)

7 (15.6)

6 (13.3)

7 (15.9)

0.919

 Dyslipidemia, n (%)

9 (20.9)

10 (22.2)

7 (16.3)

8 (17.8)

0.897

 Hepatic disease, n (%)

5 (11.6)

4 (8.9)

5 (11.6)

6 (13.6)

0.913

 Smoking, n (%)

12 (27.9)

10 (22.2)

9 (20.9)

10 (22.7)

0.892

 Preoperative PPC score

0.047 ± 0.21

0.067 ± 0.25

0.047 ± 0.21

0.046 ± 0.21

0.963

 Duration of surgery (min)

297.4 ± 102.0

285.4 ± 84.2

304.6 ± 85.6

291.5 ± 79.8

0.754

 Duration of anesthesia (min)

338.4 ± 99.6

327.4 ± 84.1

344.7 ± 85.4

331.4 ± 78.7

0.790

 Duration of CPB (min)

134.5 ± 67.9

142.9 ± 69.7

131.4 ± 58.6

137.6 ± 64.1

0.860

 Duration of ACC (min)

88.9 ± 54.9

93.6 ± 56.3

82.7 ± 47.5

83.9 ± 49.3

0.748

 Ultrafiltration (ml)

2147 ± 680.4

2078 ± 654.6

2262 ± 711.5

2209 ± 695.4

0.385

Intraoperative infusion

 Allogeneic RBC (ml)

242 ± 139.3

237 ± 121.7

229 ± 129.2

234 ± 134.2

0.975

 Plasma (ml)

388 ± 98.9

397 ± 106.2

378 ± 128.5

390 ± 141.0

0.907

 Artificial colloid fluid (ml)

963 ± 424.7

934 ± 387.9

831 ± 376.2

889 ± 376.2

0.428

 crystalloid fluid (ml)

1867 ± 565.1

1793 ± 533.2

1926 ± 507.6

1969 ± 550.2

0.452

 urine volume (ml)

976 ± 446.2

852 ± 368.3

885 ± 341.3

897 ± 375.6

0.486

 Cardiac resuscitation

    

0.542

 automatically, n (%)

35 (81.4)

33 (73.3)

33 (76.7)

30 (68.2)

 

 Defibrillation, n (%)

8 (18.6)

12 (26.7)

10 (23.3)

14 (31.8)

 

Surgical type, n (%)

 AVR, n (%)

12 (27.9)

9 (20.0)

8 (18.6)

9 (20.5)

0.745

 MVR, n (%)

11 (25.6)

11 (24.4)

11 (25.6)

10 (22.7)

0.990

 DVR, n (%)

20 (46.5)

25 (55.6)

24 (53.8)

25 (56.8)

0.760