From: Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study
Characteristics | Total (n = 76) | Delirium (n = 17) | Non-delirium (n = 59) | P value |
---|---|---|---|---|
Age (years), mean ± SD | 65.08 ± 11.14 | 66.41 ± 10.52 | 64.69 ± 11.37 | 0.565 |
Sex | 0.521 | |||
Male, n (%) | 56(73.68%) | 11(64.71%) | 45(76.27%) | |
Female, n (%) | 20(26.32%) | 6(35.29%) | 14(23.73%) | |
APACHE II | 8.80 ± 5.40 | 11.00(7.50,15.00) | 7.00(5.00,11.00) | 0.025* |
Medical history | ||||
Diabetes, n (%) | 13(17.11%) | 4(23.53%) | 9(15.25%) | 0.665 |
Hypertension, n (%) | 39(51.32%) | 10(58.82%) | 29(49.15%) | 0.482 |
History of surgery, n (%) | 37(48.68%) | 9(52.94%) | 28(47.46%) | 0.690 |
History of chemotherapy, n (%) | 19(25.00%) | 3(17.65%) | 16(27.12%) | 0.634 |
Coronary heart disease, n (%) | 4(5.26%) | 2(11.76%) | 2(3.39%) | 0.456 |
Arrhythmology, n (%) | 5(6.58%) | 1(5.88%) | 4(6.78%) | 1.000 |
Valvular disease, n (%) | 2(2.63%) | 1(5.88%) | 1(1.69%) | 0.928 |
Surgery type | 0.089 | |||
General surgery, n (%) | 30 (39.47%) | 7 (41.18%) | 23 (38.98%) | |
Thoracic surgery, n (%) | 35 (46.05%) | 5 (29.41%) | 30 (50.85%) | |
Vascular surgery, n (%) | 6 (7.89%) | 3 (17.65%) | 3 (5.08%) | |
Orthopaedics, n (%) | 2 (2.63%) | 1 (5.88%) | 1 (1.69%) | |
Urology, n (%) | 2 (2.63%) | 0 (0.00%) | 2 (3.39%) | |
Gynaecology, n (%) | 1 (1.32%) | 1 (5.88%) | 0 (0.00%) | |
Anaesthesia type | 0.060 | |||
GA | 43 (56.58%) | 13 (76.47%) | 30 (50.85%) | |
GA + EA | 33 (43.32%) | 4 (23.53%) | 29 (49.15%) | |
Intubation in OR, n (%) | 20(26.32%) | 7(41.18%) | 13(22.03%) | 0.205 |
Intubation in ICU, n (%) | 6(7.89%) | 4(23.53%) | 2(3.39%) | 0.028* |
Time of mechanical ventilation(h) | 30.19 ± 27.09 | 33.88(16.81,71.63) | 15.25(9.00,27.65) | 0.077 |
Use of sedatives | ||||
Propofol, n (%) | 21(27.63%) | 8(47.06%) | 13(22.03%) | 0.084 |
Dexmedetomidine, n (%) | 14(18.42%) | 7(41.18%) | 7(11.86%) | 0.017* |
Remifentanil, n (%) | 19(25.00%) | 7(41.18%) | 12(20.34%) | 0.153 |
Fentanyl, n (%) | 3(3.95%) | 2(11.76%) | 1(1.69%) | 0.241 |
Length of ICU stay (days) | 3.42 ± 1.90 | 4.00(3.00,6.50) | 2.00(2.00,3.00) | 0.002* |