Tissue oxygen saturation is predictive of lactate clearance in patients with circulatory shock

BMC Anesthesiology

Table 3 Area under the ROC curves for predicting 6-hour lactate clearance

Patients		AUROC (95% CI)	threshold	sensitivity	specificity
StO₂, %
masseter	all patients (n = 34)	0.65 (0.45–0.84)	71	0.95	0.33
masseter	septic shock (n = 24)	0.61 (0.37–0.85)	71	0.92	0.33
deltoid	all patients (n = 34)	0.77 (0.60–0.94)	78	0.53	0.93
deltoid	septic shock (n = 24)	0.79 (0.57–0.99)	77	0.75	0.83
thenar	all patients (n = 34)	0.72 (0.55–0.90)	73	0.47	0.93
thenar	septic shock (n = 24)	0.69 (0.48–0.91)	70	0.75	0.58
knee	all patients (n = 33)	0.87 (0.73–1.00)	71	0.74	0.93
knee	septic shock (n = 23)	0.79 (0.60–0.98)	71	0.58	0.91
weighted	all patients (n = 33)	0.92 (0.82–1.00)	72	0.84	0.93
weighted	septic shock (n = 23)	0.84 (0.67–1.00)	72	0.75	0.91
mean	all patients (n = 33)	0.85 (0.73–0.98)	72	0.89	0.71
	septic shock (n = 23)	0.81 (0.62–0.99)	74	0.58	1.00
ScvO₂, %	all patients (n = 21)	0.58 (0.27–0.89)	53	0.92	0.50
ScvO₂, %	septic shock (n = 15)	0.53 (0.17–0.88)	72	0.78	0.50
Urine output, ml/h	all patients (n = 34)	0.71 (0.54–0.89)	53	0.63	0.73
Urine output, ml/h	septic shock (n = 24)	0.70 (0.49–0.92)	80	0.5	0.92
MAP, mmHg	all patients (n = 34)	0.65 (0.45–0.84)	80	0.63	0.8
	septic shock (n = 24)	0.59 (0.34–0.84)	80	0.58	0.75

AUROC (95%CI) area under the receiver operating curves (95% Confidence Interval), PPV positive predictive value, NPV negative predictive value, StO2 tissue oxygen saturation, ScvO₂ central venous oxygen saturation, MAP mean arterial pressure

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