Tissue oxygen saturation is predictive of lactate clearance in patients with circulatory shock

BMC Anesthesiology

Table 2 Hemodynamics characteristics of patients

	All patients (n = 34)	cLac ≥ 10% (n = 19)	cLac < 10% (n = 15)	p value *
Heart rate, bpm	114 ± 22	110 ± 20	119 ± 25	0.230
MAP, mmHg	81 ± 13	79 ± 14	84 ± 12	0.308
Vasopressor
Norepinephrine, n (%)	34 (100)	19 (100)	15 (100)	1.000
Norepinephrine, µg/kg/min^¶	0.5 (0.3–1.0)	0.5 (0.3–0.9)	0.8 (0.3–1.3)	0.555
Epinephrine, n (%)	4 (12)	1 (5)	3 (20)	0.431
Epinephrine, µg/kg/min^¶	0.3 (0.2–0.3)	0.3 (0.3–0.3)	0.3 (0.2–0.3)	1.000
Urinary output, ml/h	62 ± 73	86 ± 86	32 ± 36	0.030
Lactate initial, mmol/L	6.2 ± 3.6	4.9 ± 2.0	7.7 ± 4.6	0.022
6 h- Lactate, mmol/L	6.0 ± 5.2	3.0 ± 1.3	9.9 ± 5.7	< 0.001
cLac, %	7.6 ± 45.6	39.1 ± 17.4	-32.3 ± 38.1	< 0.001
StO₂, %
masseter	73.6 ± 4.3	74.6 ± 4.0	72.4 ± 4.4	0.132
deltoid	74.9 ± 5.5	76.9 ± 4.1	72.2 ± 6.1	0.011
thenar	68.3 ± 6.6	70.8 ± 3.7	65.2 ± 8.1	0.012
knee	69.5 ± 7.2	73.1 ± 4.4	64.7 ± 7.5	< 0.001
weighted	71.0 ± 4.9	73.6 ± 2.8	67.5 ± 5.1	< 0.001
mean	71.8 ± 4.2	73.9 ± 2.6	69.1 ± 4.4	< 0.001
ScvO₂, %	64.4 ± 12.9	66.9 ± 9.4	60.3 ± 17.2	0.264

cLac Lactate clearance;MAP mean arterial pressure, StO2 tissue oxygen saturation, ScvO₂ central venous oxygen saturation
¶ Data presented as median (interquartile)
^* Comparisons were made using ANOVA test for continuous variables and Chi-Squared test for categorical variables

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