Table 2 Results of meta-analysis
Outcome indicators | Included study | Heterogeneity test results | Effect model | Results of meat analysis | ||
|---|---|---|---|---|---|---|
I2 value(%) | P value | WMD, SMD or RR(95%CI) | P value | |||
HR | 11 | 91 | P < 0.00001 | Random | 3.27(0.66,5.87) | 0.01 |
MAP | 6 | 88 | P < 0.00001 | Random | 9.68(6.13,13.24) | P < 0.00001 |
SBP | 5 | 78 | P = 0.0010 | Random | 5.42(2.11,8.73) | P = 0.001 |
DBP | 5 | 80 | P = 0.0004 | Random | 4.02(1.15,6.88) | P = 0.006 |
propofol dosage | 4 | 95 | P < 0.00001 | Random | -1.39(-2.45,-0.33) | P = 0.01 |
wake-up time | 7 | 83 | P < 0.00001 | Random | -0.55(-1.29,0.19) | P = 0.14 |
hypotension | 8 | 21 | P = 0.26 | Fixed | 0.30(0.20,0.45) | P < 0.00001 |
bradycardia | 5 | 0 | P = 0.45 | Fixed | 0.33(0.14,0.77) | P = 0.01 |
hypoxemia and apnea | 11 | 55 | P = 0.01 | Random | 0.45(0.23,0.89) | P = 0.02 |
nausea and vomiting | 7 | 0 | P = 0.65 | Fixed | 0.84(0.43,1.67) | P = 0.63 |
headache and dizziness | 5 | 36 | P = 0.18 | Fixed | 1.57(0.98,2.50) | P = 0.06 |
injection pain | 5 | 46 | P = 0.12 | Fixed | 0.28(0.13,0.60) | P = 0.001 |
intraoperative cough | 5 | 38 | P = 0.17 | Fixed | 0.62(0.50,0.77) | P < 0.0001 |
intraoperative body movements | 7 | 75 | P = 0.0005 | Random | 0.48(0.29,0.81) | P = 0.006 |
neuropsychiatric symptoms | 3 | 0 | P = 0.38 | Fixed | 1.05(0.28,3.93) | P = 0.94 |
total incidence of adverse reactions | 13 | 74 | P < 0.00001 | Random | 0.52(0.39,0.70) | P < 0.0001 |