Table 2 Logistics regression analysis of factors associated with glucocorticoid use

Age, per 1 year

0.99 (0.98–1.00)

0.033

0.99 (0.97–1.00)

0.027

Male

0.67 (0.51–0.88)

0.004

0.70 (0.51–0.96)

0.024

BMI, per 1 kg/m²

0.99 (0.98–1.02)

0.615

–

Charlson comorbidity index, per 1 score

1.07 (1.01–1.12)

0.015

1.11 (1.04–1.19)

0.003

SOFA, per 1 score

1.03 (0.99–1.09)

0.165

–

OASIS, per 1 score

1.03 (1.01–1.04)

< 0.001

0.97 (0.95–1.00)

0.024

APS III, per 1 score

1.01 (1.01–1.02)

< 0.001

1.00 (0.99–1.01)

0.420

LODS, per 1 score

1.09 (1.05–1.13)

< 0.001

1.00 (0.92–1.08)

0.959

SBP, per 1 mmHg

1.00 (0.99–1.01)

0.773

–

DBP, per 1 mmHg

1.00 (0.99–1.01)

0.830

–

Heart rate, per 1 bpm

1.01 (1.01–1.02)

< 0.001

1.01 (1.00–1.02)

0.001

Hypertension

0.93 (0.69–1.26)

0.630

–

Diabetes

0.87 (0.65–1.15)

0.319

–

Dyslipidemia

0.71 (0.54–0.94)

0.015

0.85 (0.62–1.16)

0.297

CKD

1.08 (0.82–1.44)

0.582

–

Rheumatic disease

3.46 (1.88–6.36)

< 0.001

3.61 (1.84–7.10)

< 0.001

Chronic pulmonary disease

1.72 (1.30–2.28)

< 0.001

1.61 (1.17–2.21)

0.004

ADHF

0.69 (0.53–0.91)

0.009

0.80 (0.58–1.09)

0.152

MI

0.93 (0.71–1.22)

0.596

–

Cardiac arrest

1.56 (1.08–2.26)

0.018

1.27 (0.83–1.94)

0.271

Septic shock

2.55 (1.87–3.47)

< 0.001

1.70 (1.19–2.44)

0.004

Lactate, per 1 mmol/L

1.12 (1.07–1.18)

< 0.001

1.07 (1.01–1.14)

0.024

WBC, per 1 × 10⁹/L

0.99 (0.97–1.01)

0.388

–

Platelet, per 1 × 10⁹/L

1.00 (1.00–1.00)

0.199

–

RBC, per 1 × 10¹²/L

0.88 (0.74–1.04)

0.127

–

Hemoglobin, per 1 g/L

0.96 (0.91–1.02)

0.168

–

AST, per 1 IU/L

1.00 (1.00–1.00)

0.260

–

ALT, per 1 IU/L

1.00 (1.00–1.00)

0.881

–

Albumin, per 1 g/dL

0.62 (0.49–0.78)

< 0.001

0.86 (0.66–1.11)

0.234

BUN, per 1 mg/dL

1.00 (0.99–1.00)

0.312

–

Creatinine, per 1 mg/dL

1.03 (0.95–1.13)

0.456

–

Bicarbonate, per 1 mmol/L

0.99 (0.96–1.02)

0.527

–

pH, per 0.01

0.55 (0.24–1.26)

0.155

–

BE, per 1 mmol/L

0.99 (0.99–1.00)

0.267

–

Glucose, per 1 mg/dL

1.00 (1.00–1.00)

0.020

1.00 (1.00–1.00)

0.278

Sodium, per 1 mmol/L

1.01 (0.99–1.04)

0.320

–

Potassium, per 1 mmol/L

1.07 (0.92–1.25)

0.355

–

Chloride, per 1 mmol/L

1.01 (0.99–1.03)

0.534

–

Calcium, per 1 mg/dL

0.80 (0.69–0.93)

0.003

0.94 (0.79–1.10)

0.431

Magnesium, per 1 mg/dL

0.81 (0.59–1.12)

0.202

–

INR, per 0.1

0.91 (0.80–1.04)

0.172

–

PTT, per 1 s

1.00 (0.99–1.00)

0.390

–

Antiplatelet

0.65 (0.47–0.89)

0.008

0.89 (0.59–1.34)

0.579

Statins

0.69 (0.52–0.92)

0.012

0.99 (0.67–1.44)

0.938

Inotropes

0.72 (0.54–0.97)

0.029

0.57 (0.41–0.80)

0.001

Vasopressors

1.88 (1.30–2.70)

0.001

1.15 (0.73–1.81)

0.538

MCS

1.54 (0.98–2.42)

0.060

–

CRRT

2.73 (1.97–3.79)

< 0.001

2.25 (1.51–3.34)

< 0.001

Revascularization

0.60 (0.44–0.83)

0.002

0.69 (0.48–1.01)

0.057

Mechanical ventilation

1.96 (1.45–2.66)

< 0.001

1.95 (1.25–3.04)

0.003