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Table 2 Statistical analysis of the primary and secondary outcomes of the study

From: Erector spinae plane block for perioperative pain management in neurosurgical lower-thoracic and lumbar spinal fusion: a single-centre prospective randomised controlled trial

  

ESPB

Control

p-value

missing

PCA total consumption: primary outcome (mg)

Median (25–75 IQR)

8.5 (5.5)

20 (14)

< 0.0001

-

Intraoperative fentanyl use (mcg)

   

0.021

-

Median (IQR)

200 (150)

250 (295)

-

Intraoperative blood loss (mL)

   

0.870

-

Median (IQR)

250 (100)

250 (337.5)

-

NRS

at 2 h

   

< 0.001

-

Median (IQR)

0 (1.75)

5 (2.75)

-

NRS

at 6 h

   

< 0.001

-

Median (IQR)

2 (1.75)

5 (2.75)

-

NRS

at 12 h

   

0.002

-

Median (IQR)

3 (1)

5 (1.75)

-

NRS

at 24 h

   

0.004

-

Median (IQR)

3 (2)

5 (2)

-

NRS

at 36 h

   

0.002

-

Median (IQR)

2 (1.75)

4 (1.75)

-

NRS

at 48 h

   

0.527

19

Median (IQR)

2 (1.5)

3 (1.63)

19

PCA

0–2 h (mg)

   

0.007

-

Median (IQR)

0 (0)

2 (3)

-

PCA

2–6 h (mg)

   

< 0.0001

-

Median (IQR)

1 (1.75)

3 (1.75)

-

PCA

6–12 h (mg)

   

0.002

-

Median (IQR)

2 (1)

3 (1.75)

-

PCA

12–24 h (mg)

   

0.002

-

Median (IQR)

2 (2.75)

5 (3.5)

-

PCA

24–36 h (mg)

   

0.005

-

Median (IQR)

3 (2.75)

5 (4.75)

-

PCA

36–48 h (mg)

   

0.046

13

Median (IQR)

4.5 (3.30)

3.5 (4)

13

LOS

(days)

Median (IQR)

5 (4)

7 (7)

0.226

-

Patients’ satisfaction

   

< 0.0001

-

Median (IQR)

8 (2.75)

6 (1)

-

  1. LOS, length of hospital stay; mcg, micrograms; N, absolute number; NRS, pain numeric rating scale; PCA, patient controlled analgesia (mg of morphine used at any time-interval); SD, standard deviation; IQR, interquartile range. Patients’ satisfaction is expressed with a vote from 1 (extremely bad) to 10 (extremely good) by the patient on the day of PCA pump removal. p-value refers to Mann-Whitney analysis and is considered significant when < 0.05.